282398

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 4576288..4576904 Replicon chromosome
Accession NZ_CP125781
Organism Trabulsiella odontotermitis strain TBY01

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QMG90_RS21735 Protein ID WP_283281879.1
Coordinates 4576288..4576659 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QMG90_RS21740 Protein ID WP_283281881.1
Coordinates 4576662..4576904 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG90_RS21715 (QMG90_21715) 4571629..4572972 + 1344 WP_283281874.1 VWA domain-containing protein -
QMG90_RS21720 (QMG90_21720) 4572990..4574486 + 1497 WP_283281876.1 HAMP domain-containing sensor histidine kinase -
QMG90_RS21725 (QMG90_21725) 4574491..4575177 + 687 WP_283284021.1 response regulator transcription factor -
QMG90_RS21730 (QMG90_21730) 4575320..4576249 + 930 WP_283281877.1 formate dehydrogenase accessory protein FdhE -
QMG90_RS21735 (QMG90_21735) 4576288..4576659 - 372 WP_283281879.1 type II toxin-antitoxin system VapC family toxin Toxin
QMG90_RS21740 (QMG90_21740) 4576662..4576904 - 243 WP_283281881.1 CopG family transcriptional regulator Antitoxin
QMG90_RS21745 (QMG90_21745) 4577027..4577968 - 942 WP_283284022.1 fatty acid biosynthesis protein FabY -
QMG90_RS21750 (QMG90_21750) 4578013..4578450 - 438 WP_283281883.1 D-aminoacyl-tRNA deacylase -
QMG90_RS21755 (QMG90_21755) 4578447..4579319 - 873 WP_283281885.1 virulence factor BrkB family protein -
QMG90_RS21760 (QMG90_21760) 4579313..4579912 - 600 WP_054180954.1 glucose-1-phosphatase -
QMG90_RS21765 (QMG90_21765) 4580766..4581383 + 618 WP_038161452.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-111)

Antitoxin

Ribbon-helix-helix protein, CopG

(15-49)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13543.65 Da        Isoelectric Point: 5.8431

>T282398 WP_283281879.1 NZ_CP125781:c4576659-4576288 [Trabulsiella odontotermitis]
MSGSALFDTNILIDLFSGRQAAIAALEAYPSQRAISLITWIEVMVGVPKYGDEERTKAVLELFDIIDINRDIAAKSIELR
RTHGMRLPDALILATAQVNNRSLVTRNTKDFAGIPGVVTPYQL

Download         Length: 372 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9328.69 Da        Isoelectric Point: 4.6838

>AT282398 WP_283281881.1 NZ_CP125781:c4576904-4576662 [Trabulsiella odontotermitis]
MSMVAGIDMGRILLDLSDDVIKRLDDLKQRRKLPRAELLREAVEQYLERQNRTALSDALGLWGDGVVDGLEYERKLREEW

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References