Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 4505622..4506655 | Replicon | chromosome |
| Accession | NZ_CP125781 | ||
| Organism | Trabulsiella odontotermitis strain TBY01 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | QMG90_RS21425 | Protein ID | WP_283281775.1 |
| Coordinates | 4505622..4506197 (-) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | QMG90_RS21430 | Protein ID | WP_283281777.1 |
| Coordinates | 4506197..4506655 (-) | Length | 153 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG90_RS21400 (QMG90_21400) | 4501448..4502559 | + | 1112 | WP_283281767.1 | IS3 family transposase | - |
| QMG90_RS21405 (QMG90_21405) | 4502576..4502698 | + | 123 | Protein_4169 | hydroxyacid dehydrogenase | - |
| QMG90_RS21410 (QMG90_21410) | 4503212..4505014 | + | 1803 | WP_283281769.1 | hypothetical protein | - |
| QMG90_RS21415 (QMG90_21415) | 4505031..4505222 | - | 192 | WP_283281771.1 | toxin-antitoxin system HicB family antitoxin | - |
| QMG90_RS21420 (QMG90_21420) | 4505312..4505614 | + | 303 | WP_283281773.1 | SymE family type I addiction module toxin | - |
| QMG90_RS21425 (QMG90_21425) | 4505622..4506197 | - | 576 | WP_283281775.1 | PIN domain-containing protein | Toxin |
| QMG90_RS21430 (QMG90_21430) | 4506197..4506655 | - | 459 | WP_283281777.1 | helix-turn-helix domain-containing protein | Antitoxin |
| QMG90_RS21435 (QMG90_21435) | 4506749..4507381 | - | 633 | WP_283281779.1 | helix-turn-helix domain-containing protein | - |
| QMG90_RS21440 (QMG90_21440) | 4507421..4508383 | - | 963 | WP_049848479.1 | sugar-binding transcriptional regulator | - |
| QMG90_RS21445 (QMG90_21445) | 4508473..4509258 | - | 786 | WP_283281781.1 | triose-phosphate isomerase | - |
| QMG90_RS21450 (QMG90_21450) | 4509249..4510994 | - | 1746 | WP_283281783.1 | dihydroxyacetone kinase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21632.96 Da Isoelectric Point: 5.2303
>T282397 WP_283281775.1 NZ_CP125781:c4506197-4505622 [Trabulsiella odontotermitis]
MGHSPFAVILDACVLYPARLRDLLMHLGIAGLYQPKWTEDIQGEWCRNLLRNRPDIPGEALQRTIQLMNMALPDANVTGY
EPLIESLALPDNNDRHVLAAAIRTRAEIIVTLNQKDFPPEALSSFNIEALHPDDFISDLFDLNHALVLEAVRRQRCALRH
PPITVDAFLDMLSALGLQQTTRLLNDYRYVI
MGHSPFAVILDACVLYPARLRDLLMHLGIAGLYQPKWTEDIQGEWCRNLLRNRPDIPGEALQRTIQLMNMALPDANVTGY
EPLIESLALPDNNDRHVLAAAIRTRAEIIVTLNQKDFPPEALSSFNIEALHPDDFISDLFDLNHALVLEAVRRQRCALRH
PPITVDAFLDMLSALGLQQTTRLLNDYRYVI
Download Length: 576 bp
Antitoxin
Download Length: 153 a.a. Molecular weight: 17005.55 Da Isoelectric Point: 6.6993
>AT282397 WP_283281777.1 NZ_CP125781:c4506655-4506197 [Trabulsiella odontotermitis]
MTTTVSHLNLPDSRERELAQRGQHQLTAYLSTKLETQRISIVGDDDKTHIIELPGSAMTLLVDILGELAAGNAVQIVPVQ
AELTTQEAANILNVSRPHMVKLLEQGHLPFHKIGRHRRILFADLMKYKQKREHESLDAMQALADQAQDLGML
MTTTVSHLNLPDSRERELAQRGQHQLTAYLSTKLETQRISIVGDDDKTHIIELPGSAMTLLVDILGELAAGNAVQIVPVQ
AELTTQEAANILNVSRPHMVKLLEQGHLPFHKIGRHRRILFADLMKYKQKREHESLDAMQALADQAQDLGML
Download Length: 459 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|