282393

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3426358..3426977 Replicon chromosome
Accession NZ_CP125781
Organism Trabulsiella odontotermitis strain TBY01

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag QMG90_RS16205 Protein ID WP_054180432.1
Coordinates 3426759..3426977 (+) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag QMG90_RS16200 Protein ID WP_054180431.1
Coordinates 3426358..3426732 (+) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG90_RS16190 (QMG90_16190) 3421485..3422678 + 1194 WP_283280663.1 multidrug efflux RND transporter periplasmic adaptor subunit AcrA -
QMG90_RS16195 (QMG90_16195) 3422701..3425850 + 3150 WP_283280664.1 multidrug efflux RND transporter permease subunit AcrB -
QMG90_RS16200 (QMG90_16200) 3426358..3426732 + 375 WP_054180431.1 Hha toxicity modulator TomB Antitoxin
QMG90_RS16205 (QMG90_16205) 3426759..3426977 + 219 WP_054180432.1 HHA domain-containing protein Toxin
QMG90_RS16210 (QMG90_16210) 3427186..3427647 + 462 WP_283280665.1 YlaC family protein -
QMG90_RS16215 (QMG90_16215) 3427726..3428427 + 702 WP_283280667.1 GNAT family protein -
QMG90_RS16220 (QMG90_16220) 3428647..3429675 + 1029 WP_283280668.1 isopenicillin N synthase family oxygenase -
QMG90_RS16225 (QMG90_16225) 3429696..3430502 + 807 WP_283280669.1 MetQ/NlpA family ABC transporter substrate-binding protein -
QMG90_RS16230 (QMG90_16230) 3430499..3431290 + 792 WP_283280670.1 ATP-binding cassette domain-containing protein -
QMG90_RS16235 (QMG90_16235) 3431287..3431946 + 660 WP_283280671.1 methionine ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-115)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8618.98 Da        Isoelectric Point: 8.9008

>T282393 WP_054180432.1 NZ_CP125781:3426759-3426977 [Trabulsiella odontotermitis]
MSDKPLTKNDYLLRLRRCQSIDTLERVIEKNKYELPDNELAVFYSAADHRLAELTMNKLYDKIPTSVWKFIR

Download         Length: 219 bp

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 14409.17 Da        Isoelectric Point: 4.8989

>AT282393 WP_054180431.1 NZ_CP125781:3426358-3426732 [Trabulsiella odontotermitis]
MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAVNLQLNELIEHIATFALNYKIKYNEDNKLIAQIDEYL
DDTFMLFGNYGINAEDLQKWRKSGNRLFRCFTNASRANPVSLSC

Download         Length: 375 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References