Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1817960..1818105 Replicon chromosome
Accession NZ_CP125734
Organism Klebsiella pneumoniae strain GYB02

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1817996..1818098 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1817960..1818105 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMW18_RS08780 (QMW18_08780) 1813090..1815150 + 2061 WP_004148850.1 oligopeptidase B -
QMW18_RS08785 (QMW18_08785) 1815154..1815813 - 660 WP_002911407.1 exodeoxyribonuclease X -
QMW18_RS08790 (QMW18_08790) 1815892..1816122 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QMW18_RS08795 (QMW18_08795) 1816235..1816609 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QMW18_RS08800 (QMW18_08800) 1816613..1817482 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
QMW18_RS08805 (QMW18_08805) 1817499..1817837 + 339 WP_002911404.1 YebY family protein -
- 1817960..1818105 - 146 - - Antitoxin
- 1817996..1818098 + 103 - - Toxin
QMW18_RS08810 (QMW18_08810) 1818473..1818616 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QMW18_RS08815 (QMW18_08815) 1818721..1819689 - 969 WP_014907334.1 VirK/YbjX family protein -
QMW18_RS08820 (QMW18_08820) 1819846..1820499 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
QMW18_RS08825 (QMW18_08825) 1820496..1820687 - 192 WP_002911395.1 YebW family protein -
QMW18_RS08830 (QMW18_08830) 1820785..1821024 - 240 WP_002911393.1 YebV family protein -
QMW18_RS08835 (QMW18_08835) 1821140..1822573 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T282320 NZ_CP125734:1817996-1818098 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT282320 NZ_CP125734:c1818105-1817960 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References