Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | chpSB/PRK09812-ChpS |
Location | 4219942..4220537 | Replicon | chromosome |
Accession | NZ_CP125731 | ||
Organism | Escherichia coli strain GYB01 |
Toxin (Protein)
Gene name | chpB | Uniprot ID | U9Y4M4 |
Locus tag | QMW19_RS20475 | Protein ID | WP_000239579.1 |
Coordinates | 4219942..4220292 (-) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | chpS | Uniprot ID | U9Y2K1 |
Locus tag | QMW19_RS20480 | Protein ID | WP_001223208.1 |
Coordinates | 4220286..4220537 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QMW19_RS20455 (4215388) | 4215388..4216410 | - | 1023 | WP_001295197.1 | ABC transporter permease | - |
QMW19_RS20460 (4216424) | 4216424..4217926 | - | 1503 | WP_000205784.1 | sugar ABC transporter ATP-binding protein | - |
QMW19_RS20465 (4218066) | 4218066..4219022 | - | 957 | WP_000265933.1 | galactofuranose ABC transporter substrate-binding protein YtfQ | - |
QMW19_RS20470 (4219332) | 4219332..4219862 | + | 531 | WP_000055072.1 | inorganic diphosphatase | - |
QMW19_RS20475 (4219942) | 4219942..4220292 | - | 351 | WP_000239579.1 | endoribonuclease toxin ChpB | Toxin |
QMW19_RS20480 (4220286) | 4220286..4220537 | - | 252 | WP_001223208.1 | type II toxin-antitoxin system antitoxin ChpS | Antitoxin |
QMW19_RS20485 (4220749) | 4220749..4221090 | - | 342 | WP_001219160.1 | gamma-glutamylcyclotransferase | - |
QMW19_RS20490 (4221093) | 4221093..4224872 | - | 3780 | WP_000060978.1 | autotransporter assembly complex protein TamB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12511.45 Da Isoelectric Point: 5.6219
>T282301 WP_000239579.1 NZ_CP125731:c4220292-4219942 [Escherichia coli]
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLRARLAKRIGLAADEVVEEALLRLQAVVE
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLRARLAKRIGLAADEVVEEALLRLQAVVE
Download Length: 351 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0Y8A8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9LQ26 |