Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 908083..908595 Replicon chromosome
Accession NZ_CP125718
Organism Staphylococcus casei strain DSM 15096

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag QMO72_RS04215 Protein ID WP_103266269.1
Coordinates 908392..908595 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag QMO72_RS04210 Protein ID WP_069822715.1
Coordinates 908083..908376 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMO72_RS04185 (QMO72_04185) 903178..903969 + 792 WP_103266266.1 hydroxyethylthiazole kinase -
QMO72_RS04190 (QMO72_04190) 903973..904611 + 639 WP_103266267.1 thiamine phosphate synthase -
QMO72_RS04195 (QMO72_04195) 904699..905568 + 870 WP_046837787.1 membrane protein insertase YidC -
QMO72_RS04200 (QMO72_04200) 905705..906352 - 648 WP_103266268.1 HD domain-containing protein -
QMO72_RS04205 (QMO72_04205) 906456..907940 - 1485 WP_069822716.1 cardiolipin synthase -
QMO72_RS04210 (QMO72_04210) 908083..908376 + 294 WP_069822715.1 copper-sensing transcriptional repressor CsoR Antitoxin
QMO72_RS04215 (QMO72_04215) 908392..908595 + 204 WP_103266269.1 heavy metal-associated domain-containing protein Toxin
QMO72_RS04220 (QMO72_04220) 908817..908957 + 141 WP_101118351.1 Lmo0850 family protein -
QMO72_RS04225 (QMO72_04225) 909094..910305 - 1212 WP_103266270.1 FtsW/RodA/SpoVE family cell cycle protein -
QMO72_RS04230 (QMO72_04230) 910576..911646 + 1071 WP_103266271.1 D-alanine--D-alanine ligase -
QMO72_RS04235 (QMO72_04235) 911659..913017 + 1359 WP_103266272.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Heavy metal-associated domain, HMA

(21-64)

Antitoxin

Metal-sensitive transcriptional repressor

(14-92)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 7565.66 Da        Isoelectric Point: 5.7656

>T282279 WP_103266269.1 NZ_CP125718:908392-908595 [Staphylococcus casei]
MKSKVIYVSGINNKAQQKQLEEHLKLIDGVKKVSVNQTNETISIDFETPASLNNLEKEVYDLGFTIL

Download         Length: 204 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11252.88 Da        Isoelectric Point: 6.8622

>AT282279 WP_069822715.1 NZ_CP125718:908083-908376 [Staphylococcus casei]
MEEIQKAHHSEQNKANLKSRLNRIEGQVRAINRMIDEDVYCDDVLTQIRATRSALNSVATKLLDHHMKSCIMNKVNQGQQ
EEAMEELLVTFQKLMKD

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References