Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3205381..3206024 Replicon chromosome
Accession NZ_CP125669
Organism Acinetobacter sp. KCTC 92772

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QLH32_RS15250 Protein ID WP_171062334.1
Coordinates 3205381..3205788 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QLH32_RS15255 Protein ID WP_283266889.1
Coordinates 3205791..3206024 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLH32_RS15205 (QLH32_15205) 3201337..3201717 - 381 WP_004655255.1 aspartate 1-decarboxylase -
QLH32_RS15210 (QLH32_15210) 3201863..3202444 - 582 WP_004676505.1 aminoacyl-tRNA hydrolase -
QLH32_RS15215 (QLH32_15215) 3202464..3202760 - 297 WP_004676507.1 50S ribosomal protein L25 -
QLH32_RS15220 (QLH32_15220) 3202857..3203810 - 954 WP_004676510.1 ribose-phosphate pyrophosphokinase -
QLH32_RS15245 (QLH32_15245) 3204524..3205357 - 834 WP_283269362.1 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase -
QLH32_RS15250 (QLH32_15250) 3205381..3205788 - 408 WP_171062334.1 tRNA(fMet)-specific endonuclease VapC Toxin
QLH32_RS15255 (QLH32_15255) 3205791..3206024 - 234 WP_283266889.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QLH32_RS15260 (QLH32_15260) 3206085..3206666 - 582 WP_283266891.1 lipoprotein insertase outer membrane protein LolB -
QLH32_RS15265 (QLH32_15265) 3206671..3208389 - 1719 WP_283266892.1 tetratricopeptide repeat protein -
QLH32_RS15270 (QLH32_15270) 3208469..3209752 + 1284 WP_283266894.1 glutamyl-tRNA reductase -
QLH32_RS15275 (QLH32_15275) 3209758..3210366 - 609 WP_283266896.1 Uma2 family endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

SpoVT-AbrB domain

(7-46)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15443.75 Da        Isoelectric Point: 7.1023

>T282274 WP_171062334.1 NZ_CP125669:c3205788-3205381 [Acinetobacter sp. KCTC 92772]
MLKYMLDTNICIYAIKKKPIEVIQQFSKYQDYLCISSITLMELYYGAEKSSNPQTNLTEIEKFVANLIVLDYDNYAAAHT
AQIRAELSKTGKTIGSYDAMIAGHARSQGFICVTNNIREFERVAGLRLENWWVQS

Download         Length: 408 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9026.32 Da        Isoelectric Point: 6.9801

>AT282274 WP_283266889.1 NZ_CP125669:c3206024-3205791 [Acinetobacter sp. KCTC 92772]
MEKATIFKNNRNQAVRLPKAVAFPEHIKQVEVISIGDTRILTPIGKRWELWMNTPSQLTEDCFQERDQPIAQERESF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References