Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 364343..365019 Replicon chromosome
Accession NZ_CP125669
Organism Acinetobacter sp. KCTC 92772

Toxin (Protein)


Gene name VapC1 Uniprot ID -
Locus tag QLH32_RS01700 Protein ID WP_283267788.1
Coordinates 364343..364756 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag QLH32_RS01705 Protein ID WP_283267789.1
Coordinates 364753..365019 (-) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLH32_RS01670 (QLH32_01670) 359427..360023 + 597 WP_004677443.1 recombination mediator RecR -
QLH32_RS01675 (QLH32_01675) 360316..361458 + 1143 WP_283267783.1 HRDC domain-containing protein -
QLH32_RS01680 (QLH32_01680) 361550..361855 + 306 WP_283267784.1 YcgL domain-containing protein -
QLH32_RS01685 (QLH32_01685) 361848..362234 + 387 WP_283267785.1 hypothetical protein -
QLH32_RS01690 (QLH32_01690) 362276..363127 + 852 WP_283267786.1 MoxR family ATPase -
QLH32_RS01695 (QLH32_01695) 363140..364327 + 1188 WP_283267787.1 VWA domain-containing protein -
QLH32_RS01700 (QLH32_01700) 364343..364756 - 414 WP_283267788.1 type II toxin-antitoxin system VapC family toxin Toxin
QLH32_RS01705 (QLH32_01705) 364753..365019 - 267 WP_283267789.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QLH32_RS01710 (QLH32_01710) 365206..366213 + 1008 WP_283267790.1 50S ribosomal protein L3 N(5)-glutamine methyltransferase -
QLH32_RS01715 (QLH32_01715) 366230..366598 + 369 WP_283267791.1 hypothetical protein -
QLH32_RS01720 (QLH32_01720) 366611..367702 + 1092 WP_283267792.1 chorismate synthase -
QLH32_RS01725 (QLH32_01725) 367818..369047 - 1230 WP_283267793.1 GGDEF domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-125)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 138 a.a.        Molecular weight: 15712.26 Da        Isoelectric Point: 6.8428

>T282271 WP_283267788.1 NZ_CP125669:c364756-364343 [Acinetobacter sp. KCTC 92772]
MKYMLDTNILIYFIKNKPMSVIERVNQLSQDDELCMSFISYAELLKGAYGSQRKTVVLKQLENLILRIPVLYSTQQQLCE
HYAHHALLLKQAGTPIGNNDLWIASHALAEKCILVTNNCKEFNRITDLTIENWADPA

Download         Length: 414 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10312.45 Da        Isoelectric Point: 4.4950

>AT282271 WP_283267789.1 NZ_CP125669:c365019-364753 [Acinetobacter sp. KCTC 92772]
MSTSITSRVFMNGNSQAVRIPQEFRLNTKRVEIYLNQDGDLVIHPLSDLTENRGEALWQALNEFDHDFIDTLEKNRLEDN
HIQERDVL

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References