Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4339552..4340315 Replicon chromosome
Accession NZ_CP125657
Organism Xanthomonas campestris strain GBBC 3077

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag QMY63_RS18605 Protein ID WP_283273020.1
Coordinates 4339839..4340315 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID Q8P668
Locus tag QMY63_RS18600 Protein ID WP_011038219.1
Coordinates 4339552..4339842 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMY63_RS18575 (QMY63_18575) 4335005..4335424 - 420 WP_116670568.1 pilin -
QMY63_RS18580 (QMY63_18580) 4335778..4337037 + 1260 WP_116670567.1 type II secretion system F family protein -
QMY63_RS18585 (QMY63_18585) 4337044..4337907 + 864 WP_116670566.1 A24 family peptidase -
QMY63_RS18590 (QMY63_18590) 4337921..4338544 + 624 WP_116670565.1 dephospho-CoA kinase -
QMY63_RS18595 (QMY63_18595) 4339076..4339477 + 402 WP_040940795.1 SymE family type I addiction module toxin -
QMY63_RS18600 (QMY63_18600) 4339552..4339842 + 291 WP_011038219.1 DUF1778 domain-containing protein Antitoxin
QMY63_RS18605 (QMY63_18605) 4339839..4340315 + 477 WP_283273020.1 GNAT family N-acetyltransferase Toxin
QMY63_RS18610 (QMY63_18610) 4340472..4341806 - 1335 WP_237351399.1 HAMP domain-containing sensor histidine kinase -
QMY63_RS18615 (QMY63_18615) 4341799..4342476 - 678 WP_003490678.1 response regulator transcription factor -
QMY63_RS18620 (QMY63_18620) 4343126..4344001 - 876 WP_011038222.1 30S ribosomal protein S6--L-glutamate ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 17505.09 Da        Isoelectric Point: 10.2732

>T282247 WP_283273020.1 NZ_CP125657:4339839-4340315 [Xanthomonas campestris]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKVFYERIGFEPSRWIPWCWSSRWKT

Download         Length: 477 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10678.23 Da        Isoelectric Point: 10.5480

>AT282247 WP_011038219.1 NZ_CP125657:4339552-4339842 [Xanthomonas campestris]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB Q8P668

References