Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1347339..1348117 Replicon chromosome
Accession NZ_CP125656
Organism Xanthomonas campestris strain GBBC 3139

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag QMY62_RS05655 Protein ID WP_223646366.1
Coordinates 1347339..1347830 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID Q8P668
Locus tag QMY62_RS05660 Protein ID WP_011038219.1
Coordinates 1347827..1348117 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMY62_RS05640 (QMY62_05640) 1343667..1344542 + 876 WP_011038222.1 30S ribosomal protein S6--L-glutamate ligase -
QMY62_RS05645 (QMY62_05645) 1345192..1345869 + 678 WP_003490678.1 response regulator transcription factor -
QMY62_RS05650 (QMY62_05650) 1345862..1347196 + 1335 WP_012437598.1 HAMP domain-containing sensor histidine kinase -
QMY62_RS05655 (QMY62_05655) 1347339..1347830 - 492 WP_223646366.1 GNAT family N-acetyltransferase Toxin
QMY62_RS05660 (QMY62_05660) 1347827..1348117 - 291 WP_011038219.1 DUF1778 domain-containing protein Antitoxin
QMY62_RS05665 (QMY62_05665) 1348193..1348594 - 402 WP_283269159.1 SymE family type I addiction module toxin -
QMY62_RS05670 (QMY62_05670) 1349123..1349746 - 624 WP_228424129.1 dephospho-CoA kinase -
QMY62_RS05675 (QMY62_05675) 1349760..1350623 - 864 WP_040940797.1 A24 family peptidase -
QMY62_RS05680 (QMY62_05680) 1350630..1351832 - 1203 WP_283269162.1 type II secretion system F family protein -
QMY62_RS05685 (QMY62_05685) 1352237..1352668 + 432 WP_024939397.1 pilin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1309668..1362762 53094


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17610.25 Da        Isoelectric Point: 8.1192

>T282244 WP_223646366.1 NZ_CP125656:c1347830-1347339 [Xanthomonas campestris]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLAVTLEDLK
ASL

Download         Length: 492 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10678.23 Da        Isoelectric Point: 10.5480

>AT282244 WP_011038219.1 NZ_CP125656:c1348117-1347827 [Xanthomonas campestris]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB Q8P668

References