Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1266230..1266879 Replicon chromosome
Accession NZ_CP125655
Organism Cellulomonas sp. ES6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P9841_RS05965 Protein ID WP_283321123.1
Coordinates 1266230..1266649 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P9841_RS05970 Protein ID WP_283321124.1
Coordinates 1266646..1266879 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9841_RS05940 (P9841_05940) 1261457..1262800 - 1344 WP_283321119.1 ABC transporter substrate-binding protein -
P9841_RS05945 (P9841_05945) 1262785..1263303 - 519 WP_283321120.1 hypothetical protein -
P9841_RS05950 (P9841_05950) 1263645..1264025 - 381 WP_283321872.1 MarR family transcriptional regulator -
P9841_RS05955 (P9841_05955) 1264221..1265054 + 834 WP_283321121.1 SDR family oxidoreductase -
P9841_RS05960 (P9841_05960) 1265104..1266233 - 1130 Protein_1167 methyltransferase -
P9841_RS05965 (P9841_05965) 1266230..1266649 - 420 WP_283321123.1 type II toxin-antitoxin system VapC family toxin Toxin
P9841_RS05970 (P9841_05970) 1266646..1266879 - 234 WP_283321124.1 toxin-antitoxin system Antitoxin
P9841_RS05975 (P9841_05975) 1266943..1268028 - 1086 WP_283321125.1 redox-regulated ATPase YchF -
P9841_RS05980 (P9841_05980) 1268354..1269694 - 1341 WP_283321126.1 hypothetical protein -
P9841_RS05985 (P9841_05985) 1269670..1270551 - 882 WP_283321127.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14892.04 Da        Isoelectric Point: 5.1721

>T282241 WP_283321123.1 NZ_CP125655:c1266649-1266230 [Cellulomonas sp. ES6]
MIVLDTHVISEVFRPEPEARVVAWLEGLTGEVAIAAVTLAELLAGVRRLPDGQRRTALAGMLHDALEPYRATRAILPFDV
AAAEQYADVLAARERAGRPIHTADAQIAAICLAHGATCATRNVRDFDGTGVDLVNPWTA

Download         Length: 420 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8328.48 Da        Isoelectric Point: 7.2055

>AT282241 WP_283321124.1 NZ_CP125655:c1266879-1266646 [Cellulomonas sp. ES6]
MSTIVVRGLDESVKQQLAAQAKEHGRSMEAEARDILTRAARRPHIGVALLRAARQVGGVEGLVVPERSDDARAVDLE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References