Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 542954..543621 Replicon plasmid pRspBT04f
Accession NZ_CP125651
Organism Rhizobium sp. BT04

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QMO82_RS07750 Protein ID WP_183609707.1
Coordinates 542954..543364 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QMO82_RS07755 Protein ID WP_183609706.1
Coordinates 543361..543621 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMO82_RS07730 538154..538975 + 822 WP_183609711.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
QMO82_RS07735 539075..539491 + 417 WP_183610957.1 hypothetical protein -
QMO82_RS07740 539638..540555 - 918 WP_183609709.1 hydrogen peroxide-inducible genes activator -
QMO82_RS07745 540700..542889 + 2190 WP_183609708.1 catalase/peroxidase HPI -
QMO82_RS07750 542954..543364 - 411 WP_183609707.1 type II toxin-antitoxin system VapC family toxin Toxin
QMO82_RS07755 543361..543621 - 261 WP_183609706.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QMO82_RS07760 543743..544300 - 558 WP_183609705.1 DUF3299 domain-containing protein -
QMO82_RS07765 544511..544879 - 369 WP_277545296.1 SgcJ/EcaC family oxidoreductase -
QMO82_RS07770 544800..545042 + 243 Protein_484 hypothetical protein -
QMO82_RS07775 545227..545853 + 627 WP_283196508.1 HAMP domain-containing sensor histidine kinase -
QMO82_RS07780 545856..546322 + 467 Protein_486 response regulator -
QMO82_RS07785 546334..547479 - 1146 WP_183609703.1 ROK family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd 1..659089 659089


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-126)

Antitoxin

SpoVT-AbrB domain

(8-44)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14967.23 Da        Isoelectric Point: 6.4758

>T282235 WP_183609707.1 NZ_CP125651:c543364-542954 [Rhizobium sp. BT04]
VITHLIDTNAVIALIGRKSETLLKRVIDNDEGSIGLSTVVMHELYYGAYKSAKISYNLETLRLFMAEFSVIGFEQEDALA
AGKIRAALATKGTPIGPYDVLIAAQARTRDLVLVTNNVGEFRRVDGLRVEDWTVGR

Download         Length: 411 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9917.05 Da        Isoelectric Point: 4.8723

>AT282235 WP_183609706.1 NZ_CP125651:c543621-543361 [Rhizobium sp. BT04]
MPQYARVFQSGNSQAVRLPKEFRFDVDQVEVTREGDAVILRPRAERGVRWASLHSALERGLSDDFMAEGREQPEGQERPD
LQDLFK

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References