Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 233650..234335 Replicon plasmid pRspBT03c
Accession NZ_CP125644
Organism Rhizobium sp. BT03

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QMO80_RS30660 Protein ID WP_283201320.1
Coordinates 233650..234072 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QMO80_RS30665 Protein ID WP_283201321.1
Coordinates 234069..234335 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMO80_RS30640 (QMO80_006132) 229610..230962 + 1353 WP_283201316.1 LLM class flavin-dependent oxidoreductase -
QMO80_RS30645 (QMO80_006133) 230973..231827 + 855 WP_283201317.1 ABC transporter permease -
QMO80_RS30650 (QMO80_006134) 231865..232848 + 984 WP_283201318.1 ABC transporter substrate-binding protein -
QMO80_RS30655 (QMO80_006135) 232858..233628 + 771 WP_283201319.1 ABC transporter ATP-binding protein -
QMO80_RS30660 (QMO80_006136) 233650..234072 - 423 WP_283201320.1 type II toxin-antitoxin system VapC family toxin Toxin
QMO80_RS30665 (QMO80_006137) 234069..234335 - 267 WP_283201321.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QMO80_RS30670 (QMO80_006138) 234480..236291 - 1812 WP_283201322.1 chloride channel protein -
QMO80_RS30675 (QMO80_006139) 236495..236932 + 438 WP_283201323.1 helix-turn-helix domain-containing protein -
QMO80_RS30680 (QMO80_006140) 236956..237744 - 789 WP_283201324.1 ABC transporter ATP-binding protein -
QMO80_RS30685 (QMO80_006141) 237741..238793 - 1053 WP_283201325.1 iron ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..326235 326235


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-61)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15539.83 Da        Isoelectric Point: 4.9702

>T282233 WP_283201320.1 NZ_CP125644:c234072-233650 [Rhizobium sp. BT03]
VKLLLDTNVLSEVTKPSPDARVLQWLDRLDEDRAFVSIVSVAEIRRGVALMDKGRKRDALAEWLAQDLTQRFEHRIIPVD
EPVALAWGDLMGHAKPSGRGLSSMDGLIAATAIAHDLSLATRNTRDFEGFGIELIDPWIV

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9878.13 Da        Isoelectric Point: 6.3725

>AT282233 WP_283201321.1 NZ_CP125644:c234335-234069 [Rhizobium sp. BT03]
MRLSKQGDESWTVASAKAKLSEVIERAQSAPQTITRNGKPSVIVVSAEEWQRKTARKGTLAEFLMESPLRGADLDLERQR
DEPRDPDL

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References