Detailed information of TA system TA028222

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 509792..510375
• Replicon: chromosome
• Accession: NC_018525
• Organism: Pectobacterium carotovorum subsp. carotovorum PCC21

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: PCC21_RS02305
• Protein ID: WP_014914001.1
• Coordinates: 510070..510375 (+)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: PCC21_RS02300
• Protein ID: WP_014914000.1
• Coordinates: 509792..510082 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PCC21_RS02280	504926..506188	-	1263	WP_014913996.1	L-rhamnose isomerase	-
PCC21_RS02285	506185..507675	-	1491	WP_014913997.1	rhamnulokinase	-
PCC21_RS02290	508012..508851	+	840	WP_014913998.1	HTH-type transcriptional activator RhaS	-
PCC21_RS02295	508876..509730	+	855	WP_043901800.1	helix-turn-helix domain-containing protein	-
PCC21_RS02300	509792..510082	+	291	WP_014914000.1	ribbon-helix-helix protein, CopG family	Antitoxin
PCC21_RS02305	510070..510375	+	306	WP_014914001.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PCC21_RS02310	510435..512144	-	1710	WP_014914002.1	ABC transporter ATP-binding protein	-
PCC21_RS02315	512141..513007	-	867	WP_010285293.1	ABC transporter permease	-
PCC21_RS02320	513000..513959	-	960	WP_043901801.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-96)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-46)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11662.53 Da
• Isoelectric Point: 9.4590

>T28222 WP_014914001.1 NC_018525:510070-510375 [Pectobacterium carotovorum subsp. carotovorum PCC21]
MPQVIVSERVRRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTDRVVILTVKHQKEAGYQNP

Nucleotide

• Length: 306 bp

>T28222 NC_018525:510070-510375 [Pectobacterium carotovorum subsp. carotovorum PCC21]
ATGCCACAAGTGATTGTTTCAGAACGCGTAAGACGTGATTTGCAGCGTCTGCAGGATTTTCTAAAAAACAAAAATGCGCT
GGCTGCGAAAAAGGCCGCTGAAGTTTTGATTCGCGGCATTCGTCAGTTAGAAGCGCTGCCGAATATCGGGCGACCCGTTG
AACATCTCCCTCTTGAATATCAGGAACTGGTGATCGAATTCGGCAGCAGCGGGTACGTGATGCTTTACCGTCATGATGAA
CTGACTGACAGAGTAGTGATCCTGACCGTCAAGCATCAAAAAGAAGCCGGTTACCAAAACCCTTAA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 11006.05 Da
• Isoelectric Point: 4.6327

>AT28222 WP_014914000.1 NC_018525:509792-510082 [Pectobacterium carotovorum subsp. carotovorum PCC21]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAIAEYVEREEKRSQYRKEALAAWDEYQSTGEHITADETVTWL
ESWGSGSEQDAPACHK

Nucleotide

• Length: 291 bp

>AT28222 NC_018525:509792-510082 [Pectobacterium carotovorum subsp. carotovorum PCC21]
ATGGCTGACACGCCACGCCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGTTGGCCGATGA
CCGCCATAGCTCAGCCCATGCGTTAATGCTGGAAGCCATCGCCGAATACGTGGAGCGTGAAGAAAAACGCAGTCAGTACC
GTAAAGAGGCGCTGGCCGCGTGGGATGAATACCAGAGCACCGGCGAACACATCACCGCCGATGAGACGGTCACCTGGTTA
GAATCCTGGGGTTCTGGGAGTGAACAGGATGCGCCTGCATGCCACAAGTGA