Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/Txe-YefM |
| Location | 3757716..3758245 | Replicon | chromosome |
| Accession | NZ_CP125620 | ||
| Organism | Mycobacterium tuberculosis strain BLR 4299 2019 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | G0TI95 |
| Locus tag | O3Q54_RS17710 | Protein ID | WP_003417760.1 |
| Coordinates | 3757988..3758245 (+) | Length | 86 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | G0TI94 |
| Locus tag | O3Q54_RS17705 | Protein ID | WP_003417757.1 |
| Coordinates | 3757716..3757991 (+) | Length | 92 a.a. |
Genomic Context
Location: 3756054..3756443 (390 bp)
Type: Others
Protein ID: WP_003417745.1
Type: Others
Protein ID: WP_003417745.1
Location: 3757716..3757991 (276 bp)
Type: Antitoxin
Protein ID: WP_003417757.1
Type: Antitoxin
Protein ID: WP_003417757.1
Location: 3757988..3758245 (258 bp)
Type: Toxin
Protein ID: WP_003417760.1
Type: Toxin
Protein ID: WP_003417760.1
Location: 3758287..3759477 (1191 bp)
Type: Others
Protein ID: WP_003900033.1
Type: Others
Protein ID: WP_003900033.1
Location: 3759594..3759962 (369 bp)
Type: Others
Protein ID: WP_003417765.1
Type: Others
Protein ID: WP_003417765.1
Location: 3754289..3754978 (690 bp)
Type: Others
Protein ID: WP_003917774.1
Type: Others
Protein ID: WP_003917774.1
Location: 3755165..3755536 (372 bp)
Type: Others
Protein ID: WP_003417739.1
Type: Others
Protein ID: WP_003417739.1
Location: 3755434..3755652 (219 bp)
Type: Others
Protein ID: WP_157132559.1
Type: Others
Protein ID: WP_157132559.1
Location: 3755679..3755939 (261 bp)
Type: Others
Protein ID: WP_003417741.1
Type: Others
Protein ID: WP_003417741.1
Location: 3756457..3756750 (294 bp)
Type: Others
Protein ID: WP_003417749.1
Type: Others
Protein ID: WP_003417749.1
Location: 3756747..3757592 (846 bp)
Type: Others
Protein ID: WP_003417751.1
Type: Others
Protein ID: WP_003417751.1
Location: 3759959..3760510 (552 bp)
Type: Others
Protein ID: WP_003417767.1
Type: Others
Protein ID: WP_003417767.1
Location: 3760517..3761098 (582 bp)
Type: Others
Protein ID: WP_003417769.1
Type: Others
Protein ID: WP_003417769.1
Location: 3761079..3761447 (369 bp)
Type: Others
Protein ID: WP_003417772.1
Type: Others
Protein ID: WP_003417772.1
Location: 3761425..3761817 (393 bp)
Type: Others
Protein ID: WP_003417776.1
Type: Others
Protein ID: WP_003417776.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| O3Q54_RS17670 (O3Q54_17670) | 3754289..3754978 | - | 690 | WP_003917774.1 | BBE domain-containing protein | - |
| O3Q54_RS17675 (O3Q54_17675) | 3755165..3755536 | - | 372 | WP_003417739.1 | FAD-binding protein | - |
| O3Q54_RS17680 (O3Q54_17680) | 3755434..3755652 | - | 219 | WP_157132559.1 | hypothetical protein | - |
| O3Q54_RS17685 (O3Q54_17685) | 3755679..3755939 | - | 261 | WP_003417741.1 | hypothetical protein | - |
| O3Q54_RS17690 (O3Q54_17690) | 3756054..3756443 | + | 390 | WP_003417745.1 | DUF732 domain-containing protein | - |
| O3Q54_RS17695 (O3Q54_17695) | 3756457..3756750 | - | 294 | WP_003417749.1 | DUF3017 domain-containing protein | - |
| O3Q54_RS17700 (O3Q54_17700) | 3756747..3757592 | - | 846 | WP_003417751.1 | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | - |
| O3Q54_RS17705 (O3Q54_17705) | 3757716..3757991 | + | 276 | WP_003417757.1 | type II toxin-antitoxin system antitoxin RelJ | Antitoxin |
| O3Q54_RS17710 (O3Q54_17710) | 3757988..3758245 | + | 258 | WP_003417760.1 | Txe/YoeB family addiction module toxin | Toxin |
| O3Q54_RS17715 (O3Q54_17715) | 3758287..3759477 | + | 1191 | WP_003900033.1 | NADH:flavin oxidoreductase | - |
| O3Q54_RS17720 (O3Q54_17720) | 3759594..3759962 | + | 369 | WP_003417765.1 | FHA domain-containing protein | - |
| O3Q54_RS17725 (O3Q54_17725) | 3759959..3760510 | - | 552 | WP_003417767.1 | pentapeptide repeat protein MfpA | - |
| O3Q54_RS17730 (O3Q54_17730) | 3760517..3761098 | - | 582 | WP_003417769.1 | ATP/GTP-binding protein | - |
| O3Q54_RS17735 (O3Q54_17735) | 3761079..3761447 | - | 369 | WP_003417772.1 | DUF742 domain-containing protein | - |
| O3Q54_RS17740 (O3Q54_17740) | 3761425..3761817 | - | 393 | WP_003417776.1 | serine protease inhibitor | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.