Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2423090..2423694 Replicon chromosome
Accession NZ_CP125619
Organism Pseudomonas sp. PMCC200367

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QFX16_RS11105 Protein ID WP_283183931.1
Coordinates 2423401..2423694 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID W6VBC7
Locus tag QFX16_RS11100 Protein ID WP_008153842.1
Coordinates 2423090..2423398 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFX16_RS11080 2418802..2420295 + 1494 WP_283183927.1 ATP-binding protein -
QFX16_RS11085 2420264..2421694 + 1431 WP_283183928.1 sigma-54 dependent transcriptional regulator -
QFX16_RS11090 2421698..2422084 - 387 WP_283183929.1 hypothetical protein -
QFX16_RS11095 2422264..2423076 + 813 WP_283183930.1 class I SAM-dependent methyltransferase -
QFX16_RS11100 2423090..2423398 - 309 WP_008153842.1 putative addiction module antidote protein Antitoxin
QFX16_RS11105 2423401..2423694 - 294 WP_283183931.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QFX16_RS11110 2423859..2424527 + 669 WP_283183932.1 ABC transporter ATP-binding protein -
QFX16_RS11115 2424529..2427000 + 2472 WP_283184550.1 FtsX-like permease family protein -
QFX16_RS11120 2426990..2428054 + 1065 WP_283183933.1 lipocalin-like domain-containing protein -
QFX16_RS11125 2428117..2428359 + 243 WP_283183934.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-96)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10696.48 Da        Isoelectric Point: 10.6584

>T282160 WP_283183931.1 NZ_CP125619:c2423694-2423401 [Pseudomonas sp. PMCC200367]
MNYLIQQTMIFATWHASVRDLRAKLAIARRIDRASAGNLGDIKPVGDGVSEMRVDVGAGYRVYFTMRNCVVIVLLAGGDK
SSQTADIRRAKKLAKEV

Download         Length: 294 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11017.53 Da        Isoelectric Point: 5.0344

>AT282160 WP_008153842.1 NZ_CP125619:c2423398-2423090 [Pseudomonas sp. PMCC200367]
MSQTLTTFDMAALLDSDEAISEYLSQVLADGDNEEFLRAIGYVVKARGMTQIAKDSGMGRESLYKAFAPGAKPRFDTVLK
VIHALGIDLCAQPGHSVNHSTL

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB W6VBC7

References