Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 1886026..1886642 Replicon chromosome
Accession NZ_CP125619
Organism Pseudomonas sp. PMCC200367

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag QFX16_RS08630 Protein ID WP_283183591.1
Coordinates 1886026..1886238 (+) Length 71 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag QFX16_RS08635 Protein ID WP_283183592.1
Coordinates 1886238..1886642 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFX16_RS08605 1881987..1882391 + 405 WP_283183588.1 hypothetical protein -
QFX16_RS08610 1882612..1883079 - 468 WP_283183589.1 helix-turn-helix domain-containing protein -
QFX16_RS08615 1883174..1883650 - 477 Protein_1698 LysR family transcriptional regulator -
QFX16_RS08620 1883783..1884712 - 930 WP_283180508.1 transposase -
QFX16_RS08625 1885026..1885745 - 720 WP_283183590.1 SDR family oxidoreductase -
QFX16_RS08630 1886026..1886238 + 213 WP_283183591.1 type II toxin-antitoxin system HicA family toxin Toxin
QFX16_RS08635 1886238..1886642 + 405 WP_283183592.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
QFX16_RS08640 1886703..1887908 - 1206 WP_283183593.1 MFS transporter -
QFX16_RS08645 1888222..1889220 - 999 WP_283183594.1 sulfate ABC transporter substrate-binding protein -
QFX16_RS08650 1889335..1890159 - 825 WP_283183595.1 ion transporter -
QFX16_RS08655 1890181..1891104 - 924 WP_283183596.1 urea transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(6-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-127)


Sequences

Toxin        


Download         Length: 71 a.a.        Molecular weight: 7935.20 Da        Isoelectric Point: 10.1424

>T282159 WP_283183591.1 NZ_CP125619:1886026-1886238 [Pseudomonas sp. PMCC200367]
VQSRLLIKELEEAGWILDRITGSHHLFKHRYNPYTIPVPHPKKDLPIGTVKSIRRRAGLYCPGASYAGDP

Download         Length: 213 bp

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 14761.76 Da        Isoelectric Point: 4.3841

>AT282159 WP_283183592.1 NZ_CP125619:1886238-1886642 [Pseudomonas sp. PMCC200367]
MQYPICIEWGDENTAIGIQIPDIPGAVTAGDTFEDAYNAAVEIAHIMLQEIAADGESIPMPTSAAVHRGNPDFADMGWGM
LELDIAPYMGKTEKVNVTLPGYVIQRIDRYVREHNVKSRSSFLADAAMEKLVRH

Download         Length: 405 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References