Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5676641..5678370 Replicon chromosome
Accession NZ_CP125618
Organism Pseudomonas sp. PMCC200344

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag QFW87_RS26045 Protein ID WP_283189210.1
Coordinates 5676641..5677285 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag QFW87_RS26050 Protein ID WP_283189211.1
Coordinates 5677282..5678370 (+) Length 363 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFW87_RS26010 5671822..5672634 + 813 WP_283189204.1 zinc-dependent peptidase -
QFW87_RS26015 5672748..5673275 + 528 WP_028620880.1 inorganic diphosphatase -
QFW87_RS26020 5673499..5674251 + 753 WP_283189205.1 S24 family peptidase -
QFW87_RS26025 5674841..5675185 - 345 WP_283189206.1 hypothetical protein -
QFW87_RS26030 5675236..5675898 + 663 WP_283189207.1 restriction endonuclease -
QFW87_RS26035 5676065..5676226 + 162 WP_283189208.1 hypothetical protein -
QFW87_RS26040 5676282..5676644 + 363 WP_283189209.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
QFW87_RS26045 5676641..5677285 + 645 WP_283189210.1 DUF4433 domain-containing protein Toxin
QFW87_RS26050 5677282..5678370 + 1089 WP_283189211.1 macro domain-containing protein Antitoxin
QFW87_RS26055 5678504..5679319 - 816 WP_283189212.1 DUF2135 domain-containing protein -
QFW87_RS26060 5679323..5680942 - 1620 WP_283189213.1 DUF2300 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(14-213)

Antitoxin

(18-130)


Sequences


Toxin        


Download         Length: 215 a.a.        Molecular weight: 24952.52 Da        Isoelectric Point: 6.9121

>T282153 WP_283189210.1 NZ_CP125618:5676641-5677285 [Pseudomonas sp. PMCC200344]
MNYTSLNPEKALIWRIIHRDNLPWILDNGLHCANSKVLAPQYVNIGNVDLIDKRRSRRVPIAPEGFLADYVPFYFTPFSV
MMKNIHSGWSVQQRKNDEIVILVSSLYRVEELGLPFVFTNAHAYPDWTDYYSDLANLGEIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCYSDAMKERIEQDVAARGLTLSVHARSGWYFQ

Download         Length: 645 bp


Antitoxin


Download         Length: 363 a.a.        Molecular weight: 40485.37 Da        Isoelectric Point: 5.7357

>AT282153 WP_283189211.1 NZ_CP125618:5677282-5678370 [Pseudomonas sp. PMCC200344]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAENYRLYSAACKAGAVETGKVHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLQDLRRFLIENDVKSVAVPPLGAGNGGLKWPEVREQIVDVLSDLDVDVLVFEPSNQYLNVAKRSG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKLPDTENPLNLKFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAGISDVIWFDQDRKAFLQTYLKTEAKEYSQALERTAELIDGFESPFGMELLATVDWLLNQEGVSPTVPAVREA
LSHWDGGASAAARKSKLFDDQALDIALTRLTSSSFGPVMASC

Download         Length: 1089 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References