Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 561618..562140 Replicon chromosome
Accession NZ_CP125351
Organism Escherichia fergusonii strain XJ19MCE1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QKW25_RS02690 Protein ID WP_196082280.1
Coordinates 561850..562140 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QKW25_RS02685 Protein ID WP_196082281.1
Coordinates 561618..561860 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QKW25_RS02665 (557536) 557536..558909 + 1374 WP_001219809.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase -
QKW25_RS02670 (558992) 558992..559543 - 552 WP_000166270.1 ribosome biogenesis factor YjgA -
QKW25_RS02675 (559636) 559636..560988 + 1353 WP_001162171.1 metalloprotease PmbA -
QKW25_RS02680 (561041) 561041..561427 + 387 WP_196082282.1 cytochrome b562 -
QKW25_RS02685 (561618) 561618..561860 + 243 WP_196082281.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QKW25_RS02690 (561850) 561850..562140 + 291 WP_196082280.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QKW25_RS02695 (562141) 562141..562605 - 465 WP_001106235.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
QKW25_RS02700 (562763) 562763..564901 - 2139 WP_000187805.1 anaerobic ribonucleoside-triphosphate reductase -
QKW25_RS02705 (565295) 565295..566950 - 1656 WP_283154598.1 alpha,alpha-phosphotrehalase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-68)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11293.24 Da        Isoelectric Point: 10.4221

>T282081 WP_196082280.1 NZ_CP125351:561850-562140 [Escherichia fergusonii]
MNYELAFDPRALKEWQKLGVTVREQFKKKLGDVLKRPRNPSAKLRDLPDCYKIKLRTLGYRRVYQVNDKELLVLVIAIGK
RENSAVYEDVTKRLGE

Download         Length: 291 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9140.53 Da        Isoelectric Point: 5.1369

>AT282081 WP_196082281.1 NZ_CP125351:561618-561860 [Escherichia fergusonii]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAENGRMPVKTLTVSDSEEALLRTVRERLANPQEAIKVRQDEL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References