Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2015689..2015834 Replicon chromosome
Accession NZ_CP125349
Organism Klebsiella pneumoniae strain WYKP594

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2015725..2015827 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2015689..2015834 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJR22_RS11265 (QJR22_11270) 2010819..2012879 + 2061 WP_004151449.1 oligopeptidase B -
QJR22_RS11270 (QJR22_11275) 2012883..2013542 - 660 WP_002911407.1 exodeoxyribonuclease X -
QJR22_RS11275 (QJR22_11280) 2013621..2013851 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QJR22_RS11280 (QJR22_11285) 2013964..2014338 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QJR22_RS11285 (QJR22_11290) 2014342..2015211 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
QJR22_RS11290 (QJR22_11295) 2015228..2015566 + 339 WP_002911404.1 YebY family protein -
- 2015689..2015834 - 146 - - Antitoxin
- 2015725..2015827 + 103 - - Toxin
QJR22_RS11295 (QJR22_11300) 2016202..2016345 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QJR22_RS11300 (QJR22_11305) 2016450..2017418 - 969 WP_004151446.1 VirK/YbjX family protein -
QJR22_RS11305 (QJR22_11310) 2017575..2018228 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QJR22_RS11310 (QJR22_11315) 2018225..2018416 - 192 WP_002911395.1 YebW family protein -
QJR22_RS11315 (QJR22_11320) 2018514..2018753 - 240 WP_002911393.1 YebV family protein -
QJR22_RS11320 (QJR22_11325) 2018869..2020302 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T282069 NZ_CP125349:2015725-2015827 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT282069 NZ_CP125349:c2015834-2015689 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References