Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2013582..2013727 Replicon chromosome
Accession NZ_CP125343
Organism Klebsiella pneumoniae strain WYKP589

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2013618..2013720 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2013582..2013727 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJR23_RS11235 (QJR23_11235) 2008712..2010772 + 2061 WP_004151449.1 oligopeptidase B -
QJR23_RS11240 (QJR23_11240) 2010776..2011435 - 660 WP_002911407.1 exodeoxyribonuclease X -
QJR23_RS11245 (QJR23_11245) 2011514..2011744 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QJR23_RS11250 (QJR23_11250) 2011857..2012231 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QJR23_RS11255 (QJR23_11255) 2012235..2013104 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
QJR23_RS11260 (QJR23_11260) 2013121..2013459 + 339 WP_002911404.1 YebY family protein -
- 2013582..2013727 - 146 - - Antitoxin
- 2013618..2013720 + 103 - - Toxin
QJR23_RS11265 (QJR23_11265) 2014095..2014238 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QJR23_RS11270 (QJR23_11270) 2014343..2015311 - 969 WP_004151446.1 VirK/YbjX family protein -
QJR23_RS11275 (QJR23_11275) 2015468..2016121 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QJR23_RS11280 (QJR23_11280) 2016118..2016309 - 192 WP_002911395.1 YebW family protein -
QJR23_RS11285 (QJR23_11285) 2016407..2016646 - 240 WP_002911393.1 YebV family protein -
QJR23_RS11290 (QJR23_11290) 2016762..2018195 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T282042 NZ_CP125343:2013618-2013720 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT282042 NZ_CP125343:c2013727-2013582 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References