Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2026829..2026974 Replicon chromosome
Accession NC_018522
Organism Klebsiella pneumoniae subsp. pneumoniae 1084

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2026865..2026967 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2026829..2026974 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A79E_RS09615 2021958..2024018 + 2061 WP_004151449.1 oligopeptidase B -
A79E_RS09620 2024022..2024681 - 660 WP_002911407.1 exodeoxyribonuclease X -
A79E_RS09625 2024760..2024991 - 232 Protein_1868 DNA polymerase III subunit theta -
A79E_RS09630 2025104..2025478 + 375 WP_004151448.1 CopC domain-containing protein YobA -
A79E_RS09635 2025482..2026351 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
A79E_RS09640 2026368..2026706 + 339 WP_002911404.1 YebY family protein -
- 2026829..2026974 - 146 - - Antitoxin
- 2026865..2026967 + 103 - - Toxin
A79E_RS28425 2027341..2027484 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
A79E_RS09650 2027589..2028557 - 969 WP_014907334.1 VirK/YbjX family protein -
A79E_RS09655 2028714..2029367 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
A79E_RS09660 2029364..2029555 - 192 WP_002911395.1 YebW family protein -
A79E_RS09665 2029653..2029892 - 240 WP_002911393.1 YebV family protein -
A79E_RS09670 2030008..2031441 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T28204 NC_018522:2026865-2026967 [Klebsiella pneumoniae subsp. pneumoniae 1084]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT28204 NC_018522:c2026974-2026829 [Klebsiella pneumoniae subsp. pneumoniae 1084]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References