Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2008154..2008299 Replicon chromosome
Accession NZ_CP125334
Organism Klebsiella pneumoniae strain WYKP586

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2008190..2008292 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2008154..2008299 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJR21_RS09865 (QJR21_09865) 2003284..2005344 + 2061 WP_004151449.1 oligopeptidase B -
QJR21_RS09870 (QJR21_09870) 2005348..2006007 - 660 WP_002911407.1 exodeoxyribonuclease X -
QJR21_RS09875 (QJR21_09875) 2006086..2006316 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QJR21_RS09880 (QJR21_09880) 2006429..2006803 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QJR21_RS09885 (QJR21_09885) 2006807..2007676 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
QJR21_RS09890 (QJR21_09890) 2007693..2008031 + 339 WP_002911404.1 YebY family protein -
- 2008154..2008299 - 146 - - Antitoxin
- 2008190..2008292 + 103 - - Toxin
QJR21_RS09895 (QJR21_09895) 2008667..2008810 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QJR21_RS09900 (QJR21_09900) 2008915..2009883 - 969 WP_004151446.1 VirK/YbjX family protein -
QJR21_RS09905 (QJR21_09905) 2010040..2010693 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QJR21_RS09910 (QJR21_09910) 2010690..2010881 - 192 WP_002911395.1 YebW family protein -
QJR21_RS09915 (QJR21_09915) 2010979..2011218 - 240 WP_002911393.1 YebV family protein -
QJR21_RS09920 (QJR21_09920) 2011334..2012767 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T282009 NZ_CP125334:2008190-2008292 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT282009 NZ_CP125334:c2008299-2008154 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References