Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907(toxin)
Location 2403517..2404082 Replicon chromosome
Accession NZ_CP125315
Organism Lacticaseibacillus rhamnosus strain k32

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QJQ50_RS11135 Protein ID WP_032964763.1
Coordinates 2403517..2403864 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QJQ50_RS11140 Protein ID WP_225350938.1
Coordinates 2403864..2404082 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJQ50_RS11115 (QJQ50_11115) 2399133..2400374 - 1242 WP_048482391.1 acyltransferase -
QJQ50_RS11120 (QJQ50_11120) 2400371..2401072 - 702 WP_032964765.1 ATP-binding cassette domain-containing protein -
QJQ50_RS11125 (QJQ50_11125) 2401065..2401883 - 819 WP_048482390.1 ABC transporter permease subunit -
QJQ50_RS11130 (QJQ50_11130) 2402124..2402792 - 669 WP_005711196.1 phenylalanine--tRNA ligase beta subunit-related protein -
QJQ50_RS11135 (QJQ50_11135) 2403517..2403864 - 348 WP_032964763.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QJQ50_RS11140 (QJQ50_11140) 2403864..2404082 - 219 WP_225350938.1 transcription elongation factor GreAB Antitoxin
QJQ50_RS11145 (QJQ50_11145) 2404176..2406011 - 1836 WP_048482389.1 ABC transporter ATP-binding protein -
QJQ50_RS11150 (QJQ50_11150) 2405998..2407788 - 1791 WP_048482388.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-97)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 13148.08 Da        Isoelectric Point: 9.3929

>T282003 WP_032964763.1 NZ_CP125315:c2403864-2403517 [Lacticaseibacillus rhamnosus]
MTYKAKPGDVVWLDFDPSKGHEIRKRCPAVVLSSNAYNRATGFVIVSPITSTIRTLPGYVDIVSNKIRGQIVTSQVYSLD
VTEQGNRKIDFIERMNIEDFYTVAQFTKMNFDFKF

Download         Length: 348 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8107.29 Da        Isoelectric Point: 5.7995

>AT282003 WP_225350938.1 NZ_CP125315:c2404082-2403864 [Lacticaseibacillus rhamnosus]
MMDVKVVKRGNSLALSLPSSAGFKRGEAFLLISDEKGGYLLIPKVKNPYTKAKSLSFHQEEAWPDFDYEDIE

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References