Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3052519..3052660 Replicon chromosome
Accession NZ_CP125310
Organism Citrobacter freundii strain CF5125

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3052522..3052625 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3052519..3052660 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QKW62_RS15220 3047787..3048002 + 216 WP_057064237.1 hypothetical protein -
QKW62_RS15225 3048048..3048386 + 339 WP_283146379.1 Rrf2 family transcriptional regulator -
QKW62_RS15230 3048528..3051008 + 2481 WP_283146380.1 3'-5' exoribonuclease -
QKW62_RS15235 3051072..3051332 + 261 WP_072211989.1 excisionase -
QKW62_RS15240 3051310..3052389 + 1080 WP_283146381.1 phage integrase Arm DNA-binding domain-containing protein -
- 3052519..3052660 + 142 - - Antitoxin
- 3052522..3052625 - 104 - - Toxin
QKW62_RS15245 3052781..3053119 - 339 WP_003034934.1 YebY family protein -
QKW62_RS15250 3053140..3054012 - 873 WP_283146382.1 copper homeostasis membrane protein CopD -
QKW62_RS15255 3054016..3054390 - 375 WP_003034928.1 CopC domain-containing protein YobA -
QKW62_RS15260 3054534..3054764 + 231 WP_003034925.1 DNA polymerase III subunit theta -
QKW62_RS15265 3054871..3055527 + 657 WP_003841657.1 carbon-nitrogen hydrolase family protein -
QKW62_RS15270 3055551..3056213 + 663 WP_003833802.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2955862..3058282 102420


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T281980 NZ_CP125310:c3052625-3052522 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 142 bp

>AT281980 NZ_CP125310:3052519-3052660 [Citrobacter freundii]
GATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGG
CATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References