Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 4121583..4122108 Replicon chromosome
Accession NZ_CP125300
Organism Pseudomonas syringae pv. syringae strain B48

Toxin (Protein)


Gene name stbE Uniprot ID Q4ZPQ9
Locus tag QMB36_RS17490 Protein ID WP_011268681.1
Coordinates 4121818..4122108 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q4ZPR0
Locus tag QMB36_RS17485 Protein ID WP_003402372.1
Coordinates 4121583..4121828 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMB36_RS17480 (QMB36_17475) 4117498..4121409 - 3912 WP_054092157.1 ATP-dependent RNA helicase HrpA -
QMB36_RS17485 (QMB36_17480) 4121583..4121828 + 246 WP_003402372.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QMB36_RS17490 (QMB36_17485) 4121818..4122108 + 291 WP_011268681.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMB36_RS17495 (QMB36_17490) 4122426..4124117 - 1692 WP_011268682.1 long-chain-fatty-acid--CoA ligase FadD1 -
QMB36_RS17500 (QMB36_17495) 4124472..4126160 - 1689 WP_054092158.1 long-chain-fatty-acid--CoA ligase FadD2 -
QMB36_RS17505 (QMB36_17500) 4126529..4126999 + 471 WP_003402365.1 MaoC family dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11010.01 Da        Isoelectric Point: 10.7294

>T281974 WP_011268681.1 NZ_CP125300:4121818-4122108 [Pseudomonas syringae pv. syringae]
MTFKLEFLPSALKEWEKLGHTIRVQLKKKLLERLGLPRIPGDALHGMPDHYKIKLRSAGYRLVYRVEEDRVVVTVVAVGK
RERGNIYDSAKGRLGP

Download         Length: 291 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8827.22 Da        Isoelectric Point: 4.5349

>AT281974 WP_003402372.1 NZ_CP125300:4121583-4121828 [Pseudomonas syringae pv. syringae]
MQSILADVAVSVSELKKNPSAVLSGAHGLPVAVLNHNKVMGYMVPAEVFEAMMERLDDLDLAELIKSRQHEKPVSVDIDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q4ZPQ9

Antitoxin

Source ID Structure
AlphaFold DB A0A3M2V2W1

References