Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 1593314..1593829 Replicon chromosome
Accession NZ_CP125290
Organism Micrococcus yunnanensis strain TJPT4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QL063_RS07270 Protein ID WP_141843596.1
Coordinates 1593314..1593568 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QL063_RS07275 Protein ID WP_141843594.1
Coordinates 1593569..1593829 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QL063_RS07240 (QL063_07240) 1588832..1590238 + 1407 WP_119217901.1 Dyp-type peroxidase -
QL063_RS07245 (QL063_07245) 1590235..1590624 + 390 WP_141843602.1 hypothetical protein -
QL063_RS07250 (QL063_07250) 1590656..1591381 + 726 WP_181743493.1 histidine phosphatase family protein -
QL063_RS07255 (QL063_07255) 1591378..1591920 + 543 WP_101967565.1 DUF3090 domain-containing protein -
QL063_RS07260 (QL063_07260) 1591920..1592702 + 783 WP_141843600.1 SCO1664 family protein -
QL063_RS07265 (QL063_07265) 1592746..1593312 - 567 WP_141843598.1 mismatch-specific DNA-glycosylase -
QL063_RS07270 (QL063_07270) 1593314..1593568 - 255 WP_141843596.1 Txe/YoeB family addiction module toxin Toxin
QL063_RS07275 (QL063_07275) 1593569..1593829 - 261 WP_141843594.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QL063_RS07280 (QL063_07280) 1594054..1595397 - 1344 WP_044658726.1 IS256-like element ISMlu11 family transposase -
QL063_RS07285 (QL063_07285) 1595695..1596240 - 546 WP_141844277.1 hypothetical protein -
QL063_RS07290 (QL063_07290) 1596620..1596769 + 150 WP_181743517.1 hypothetical protein -
QL063_RS07295 (QL063_07295) 1596991..1598133 - 1143 WP_141844278.1 CHAT domain-containing protein -
QL063_RS07300 (QL063_07300) 1598530..1598631 + 102 Protein_1412 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1594054..1595403 1349


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9873.20 Da        Isoelectric Point: 7.3149

>T281963 WP_141843596.1 NZ_CP125290:c1593568-1593314 [Micrococcus yunnanensis]
VRLVWDRSAWEDYMHWQTTDRKGLTRINTLVDAALRDPFEGIGKPGQLKYGAAGAWSRRITEEHRLVYLVDGEDLIVLQV
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9607.72 Da        Isoelectric Point: 4.8359

>AT281963 WP_141843594.1 NZ_CP125290:c1593829-1593569 [Micrococcus yunnanensis]
MSISASEARKTLFPLIERVNADRDAVEIVSRRGNAVLMPADEYAAWQETAYLFRSPANARRLLDAYERARAGSVEEHALD
RLDGDA

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References