Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 75233..75886 Replicon chromosome
Accession NZ_CP125227
Organism Acinetobacter pittii strain SO1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OH685_RS00390 Protein ID WP_086399324.1
Coordinates 75233..75622 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A009HHW9
Locus tag OH685_RS00395 Protein ID WP_002117064.1
Coordinates 75629..75886 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH685_RS00375 (OH685_00370) 70339..72534 - 2196 WP_005067292.1 TRAP transporter large permease subunit -
OH685_RS00380 (OH685_00375) 72714..73289 - 576 WP_005067290.1 rhombosortase -
OH685_RS00385 (OH685_00380) 73374..74462 - 1089 WP_202744799.1 hypothetical protein -
OH685_RS00390 (OH685_00390) 75233..75622 - 390 WP_086399324.1 hypothetical protein Toxin
OH685_RS00395 (OH685_00395) 75629..75886 - 258 WP_002117064.1 succinate dehydrogenase assembly factor 2 Antitoxin
OH685_RS00400 (OH685_00400) 76075..77247 + 1173 WP_282463629.1 acyl-CoA dehydrogenase family protein -
OH685_RS00405 (OH685_00405) 77298..78788 - 1491 WP_002116796.1 NAD(P)/FAD-dependent oxidoreductase -
OH685_RS00410 (OH685_00410) 78970..79347 - 378 WP_002049717.1 50S ribosomal protein L17 -
OH685_RS00415 (OH685_00415) 79366..80373 - 1008 WP_002116730.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15586.65 Da        Isoelectric Point: 6.3102

>T281950 WP_086399324.1 NZ_CP125227:c75622-75233 [Acinetobacter pittii]
MIKELNFELKYSRVSVVFQLFVGLGLAILLYQLLTPMWWLCAVILLFIGFIFFLKQVQISQIEYLDQKLWSVAYFSEKEI
YRAEITKIIDYQLFVVIYFEETPTNIAIVWFDQLPIQQWKRLKVLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10295.73 Da        Isoelectric Point: 4.4809

>AT281950 WP_002117064.1 NZ_CP125227:c75886-75629 [Acinetobacter pittii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A009HHW9

References