Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | BrnTA/BrnT-BrnA |
Location | 5666..6254 | Replicon | plasmid unnamed |
Accession | NZ_CP125226 | ||
Organism | Acinetobacter baumannii strain EGA10 |
Toxin (Protein)
Gene name | brnT | Uniprot ID | A0A0J8TIH5 |
Locus tag | QMA75_RS18775 | Protein ID | WP_000438827.1 |
Coordinates | 5666..5953 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | brnA | Uniprot ID | N9M5I3 |
Locus tag | QMA75_RS18780 | Protein ID | WP_001983304.1 |
Coordinates | 5940..6254 (+) | Length | 105 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QMA75_RS18745 (QMA75_18745) | 944..1519 | + | 576 | WP_001096611.1 | plasmid replication DNA-binding protein | - |
QMA75_RS18750 (QMA75_18750) | 1541..1684 | + | 144 | WP_000734097.1 | hypothetical protein | - |
QMA75_RS18755 (QMA75_18755) | 1991..2266 | + | 276 | WP_001133626.1 | metal/formaldehyde-sensitive transcriptional repressor | - |
QMA75_RS18760 (QMA75_18760) | 2288..3397 | + | 1110 | WP_000842148.1 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase | - |
QMA75_RS18765 (QMA75_18765) | 3450..3848 | + | 399 | WP_000235176.1 | VOC family protein | - |
QMA75_RS18770 (QMA75_18770) | 4322..5155 | + | 834 | WP_000439570.1 | S-formylglutathione hydrolase | - |
QMA75_RS18775 (QMA75_18775) | 5666..5953 | + | 288 | WP_000438827.1 | BrnT family toxin | Toxin |
QMA75_RS18780 (QMA75_18780) | 5940..6254 | + | 315 | WP_001983304.1 | BrnA antitoxin family protein | Antitoxin |
QMA75_RS18785 (QMA75_18785) | 6382..8793 | + | 2412 | WP_000932953.1 | TonB-dependent receptor ZnuD2 | - |
QMA75_RS18790 (QMA75_18790) | 9098..9559 | + | 462 | WP_000761346.1 | DIP1984 family protein | - |
QMA75_RS18795 (QMA75_18795) | 9880..10413 | - | 534 | WP_000965055.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..14639 | 14639 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0J8TIH5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | N9M5I3 |