Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 455814..456467 Replicon chromosome
Accession NZ_CP125225
Organism Acinetobacter baumannii strain EGA10

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QMA75_RS02235 Protein ID WP_000607077.1
Coordinates 456078..456467 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag QMA75_RS02230 Protein ID WP_001288210.1
Coordinates 455814..456071 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMA75_RS02210 (QMA75_02210) 451330..452337 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
QMA75_RS02215 (QMA75_02215) 452356..452733 + 378 WP_001216380.1 50S ribosomal protein L17 -
QMA75_RS02220 (QMA75_02220) 452915..454405 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
QMA75_RS02225 (QMA75_02225) 454454..455626 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
QMA75_RS02230 (QMA75_02230) 455814..456071 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
QMA75_RS02235 (QMA75_02235) 456078..456467 + 390 WP_000607077.1 membrane protein Toxin
QMA75_RS02240 (QMA75_02240) 457237..458322 + 1086 WP_000049106.1 hypothetical protein -
QMA75_RS02245 (QMA75_02245) 458400..458966 + 567 WP_000651538.1 rhombosortase -
QMA75_RS02250 (QMA75_02250) 459154..461349 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T281947 WP_000607077.1 NZ_CP125225:456078-456467 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT281947 WP_001288210.1 NZ_CP125225:455814-456071 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References