Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 454087..454740 Replicon chromosome
Accession NZ_CP125223
Organism Acinetobacter baumannii strain EGA65

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QMA76_RS02220 Protein ID WP_000607077.1
Coordinates 454351..454740 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag QMA76_RS02215 Protein ID WP_001288210.1
Coordinates 454087..454344 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMA76_RS02195 (QMA76_02195) 449603..450610 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
QMA76_RS02200 (QMA76_02200) 450629..451006 + 378 WP_001216380.1 50S ribosomal protein L17 -
QMA76_RS02205 (QMA76_02205) 451188..452678 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
QMA76_RS02210 (QMA76_02210) 452727..453899 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
QMA76_RS02215 (QMA76_02215) 454087..454344 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
QMA76_RS02220 (QMA76_02220) 454351..454740 + 390 WP_000607077.1 membrane protein Toxin
QMA76_RS02225 (QMA76_02225) 455510..456595 + 1086 WP_000049106.1 hypothetical protein -
QMA76_RS02230 (QMA76_02230) 456673..457239 + 567 WP_000651538.1 rhombosortase -
QMA76_RS02235 (QMA76_02235) 457427..459622 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T281944 WP_000607077.1 NZ_CP125223:454351-454740 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT281944 WP_001288210.1 NZ_CP125223:454087-454344 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References