Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2034723..2034868 Replicon chromosome
Accession NZ_CP125088
Organism Klebsiella pneumoniae strain BAK085

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2034759..2034861 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2034723..2034868 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJS47_RS09980 (QJS47_09980) 2029853..2031913 + 2061 WP_004151449.1 oligopeptidase B -
QJS47_RS09985 (QJS47_09985) 2031917..2032576 - 660 WP_002911407.1 exodeoxyribonuclease X -
QJS47_RS09990 (QJS47_09990) 2032655..2032885 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QJS47_RS09995 (QJS47_09995) 2032998..2033372 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QJS47_RS10000 (QJS47_10000) 2033376..2034245 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
QJS47_RS10005 (QJS47_10005) 2034262..2034600 + 339 WP_002911404.1 YebY family protein -
- 2034723..2034868 - 146 - - Antitoxin
- 2034759..2034861 + 103 - - Toxin
QJS47_RS10010 (QJS47_10010) 2035236..2035379 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QJS47_RS10015 (QJS47_10015) 2035484..2036452 - 969 WP_004151446.1 VirK/YbjX family protein -
QJS47_RS10020 (QJS47_10020) 2036609..2037262 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QJS47_RS10025 (QJS47_10025) 2037259..2037450 - 192 WP_002911395.1 YebW family protein -
QJS47_RS10030 (QJS47_10030) 2037548..2037787 - 240 WP_002911393.1 YebV family protein -
QJS47_RS10035 (QJS47_10035) 2037903..2039336 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T281902 NZ_CP125088:2034759-2034861 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT281902 NZ_CP125088:c2034868-2034723 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References