Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 906187..906332 Replicon chromosome
Accession NZ_CP125086
Organism Klebsiella pneumoniae subsp. pneumoniae strain HVKP2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 906223..906325 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 906187..906332 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFB74_RS05460 901317..903377 + 2061 WP_004151449.1 oligopeptidase B -
QFB74_RS05465 903381..904040 - 660 WP_002911407.1 exodeoxyribonuclease X -
QFB74_RS05470 904119..904349 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QFB74_RS05475 904462..904836 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QFB74_RS05480 904840..905709 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
QFB74_RS05485 905726..906064 + 339 WP_002911404.1 YebY family protein -
- 906187..906332 - 146 - - Antitoxin
- 906223..906325 + 103 - - Toxin
QFB74_RS05490 906700..906843 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QFB74_RS05495 906948..907916 - 969 WP_014907334.1 VirK/YbjX family protein -
QFB74_RS05500 908073..908726 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QFB74_RS05505 908723..908914 - 192 WP_002911395.1 YebW family protein -
QFB74_RS05510 909012..909251 - 240 WP_002911393.1 YebV family protein -
QFB74_RS05515 909367..910800 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T281887 NZ_CP125086:906223-906325 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT281887 NZ_CP125086:c906332-906187 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References