Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 67199..67734 Replicon plasmid p_IncFIA_HI1
Accession NZ_CP125084
Organism Klebsiella pneumoniae subsp. pneumoniae strain HVKP1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QFB57_RS26660 Protein ID WP_016531292.1
Coordinates 67199..67486 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID W9BAK2
Locus tag QFB57_RS26665 Protein ID WP_016531291.1
Coordinates 67483..67734 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFB57_RS26640 62998..64218 - 1221 WP_032446666.1 ISL3-like element ISKox3 family transposase -
QFB57_RS26645 64379..64855 + 477 WP_016529487.1 hypothetical protein -
QFB57_RS26650 65112..65399 - 288 WP_016529486.1 hypothetical protein -
QFB57_RS26655 65489..66151 - 663 WP_016529485.1 division plane positioning ATPase MipZ -
QFB57_RS26660 67199..67486 - 288 WP_016531292.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QFB57_RS26665 67483..67734 - 252 WP_016531291.1 toxin-antitoxin stability system antitoxin protein StbD Antitoxin
QFB57_RS26670 67830..69101 - 1272 WP_046041953.1 Y-family DNA polymerase -
QFB57_RS26675 69101..69595 - 495 WP_109234271.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
QFB57_RS26680 69581..70660 + 1080 WP_016531016.1 IS481 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - clbI / basG 1..95433 95433
- flank IS/Tn - - 62998..64218 1220


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11120.16 Da        Isoelectric Point: 10.4373

>T281883 WP_016531292.1 NZ_CP125084:c67486-67199 [Klebsiella pneumoniae subsp. pneumoniae]
MTYTVKFREDALKEWNKLDKTIQQQFAKKLKKCCENPHIPSAKLRGIKDCYKIKLRASGFRLVYQVIDNQLIIAIVAVGK
RERSDVYTLASERMK

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9285.68 Da        Isoelectric Point: 4.2257

>AT281883 WP_016531291.1 NZ_CP125084:c67734-67483 [Klebsiella pneumoniae subsp. pneumoniae]
MPHIILSDTTASVSELKKNPMATVSAGDGFPVAILNRNQPAFYCVPAELYEKMLDALDDQELIKLVAERSNQPLFDMDLE
KYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB W9BAK2

References