Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 442037..442581 Replicon chromosome
Accession NZ_CP124967
Organism Agrobacterium tumefaciens strain O54/95

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G6L90_RS02140 Protein ID WP_173992172.1
Coordinates 442291..442581 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A822V4A8
Locus tag G6L90_RS02135 Protein ID WP_003509084.1
Coordinates 442037..442288 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L90_RS02115 (G6L90_02115) 437800..438480 + 681 WP_003509096.1 GntR family transcriptional regulator -
G6L90_RS02120 (G6L90_02120) 438526..439002 + 477 WP_107675263.1 DUF1284 domain-containing protein -
G6L90_RS02125 (G6L90_02125) 439177..440277 - 1101 WP_087743497.1 hypothetical protein -
G6L90_RS02130 (G6L90_02130) 440514..441659 + 1146 WP_020010628.1 site-specific DNA-methyltransferase -
G6L90_RS02135 (G6L90_02135) 442037..442288 + 252 WP_003509084.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
G6L90_RS02140 (G6L90_02140) 442291..442581 + 291 WP_173992172.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L90_RS02145 (G6L90_02145) 442623..443234 - 612 WP_087743505.1 HAD family phosphatase -
G6L90_RS02150 (G6L90_02150) 443231..444343 - 1113 WP_099085591.1 A/G-specific adenine glycosylase -
G6L90_RS02155 (G6L90_02155) 444471..444935 + 465 WP_020812858.1 hypothetical protein -
G6L90_RS02160 (G6L90_02160) 444963..445484 + 522 WP_003509079.1 DUF721 domain-containing protein -
G6L90_RS02165 (G6L90_02165) 445613..446293 + 681 WP_003509078.1 DsbA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(12-70)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11225.88 Da        Isoelectric Point: 6.2182

>T281858 WP_173992172.1 NZ_CP124967:442291-442581 [Agrobacterium tumefaciens]
VGFRLSLLAEEDVIRIAEEGIAIFGLAQAQKYHRELYEIFELISLNPRMARERHELLPPLRIHRFRTHLVVYGVGADDDV
LIVRVRHAHEDWVNES

Download         Length: 291 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9339.55 Da        Isoelectric Point: 9.7317

>AT281858 WP_003509084.1 NZ_CP124967:442037-442288 [Agrobacterium tumefaciens]
MATMNISLPAPMKEWVEAQSRTGRYSNASDYVRDLIRKDQERGEKIAAMQHFVDEGLQSGAGHRSQQALFAEAEARSMKR
KIG

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A822V4A8

References