281857

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 321153..321639 Replicon chromosome
Accession NZ_CP124967
Organism Agrobacterium tumefaciens strain O54/95

Toxin (Protein)


Gene name pasB Uniprot ID A0A846L580
Locus tag G6L90_RS01520 Protein ID WP_003503189.1
Coordinates 321153..321422 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A822V377
Locus tag G6L90_RS01525 Protein ID WP_003503188.1
Coordinates 321406..321639 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L90_RS01485 (G6L90_01485) 316175..316804 + 630 WP_003503196.1 DNA-3-methyladenine glycosylase I -
G6L90_RS01490 (G6L90_01490) 316801..317247 + 447 WP_060726047.1 hypothetical protein -
G6L90_RS01495 (G6L90_01495) 317263..318306 - 1044 WP_065694890.1 YeiH family protein -
G6L90_RS01500 (G6L90_01500) 318388..319305 + 918 WP_026363679.1 LysR substrate-binding domain-containing protein -
G6L90_RS01505 (G6L90_01505) 319516..319890 - 375 WP_129564593.1 DUF305 domain-containing protein -
G6L90_RS01510 (G6L90_01510) 319948..320340 - 393 WP_003503191.1 hypothetical protein -
G6L90_RS01515 (G6L90_01515) 320382..321146 - 765 WP_003503190.1 hypothetical protein -
G6L90_RS01520 (G6L90_01520) 321153..321422 - 270 WP_003503189.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L90_RS01525 (G6L90_01525) 321406..321639 - 234 WP_003503188.1 DUF6290 family protein Antitoxin
G6L90_RS01530 (G6L90_01530) 321797..323320 + 1524 WP_174069498.1 histidine--tRNA ligase -
G6L90_RS01535 (G6L90_01535) 323325..323693 + 369 WP_111833685.1 VOC family protein -
G6L90_RS01540 (G6L90_01540) 323710..324837 + 1128 WP_111781269.1 ATP phosphoribosyltransferase regulatory subunit -
G6L90_RS01545 (G6L90_01545) 324834..325526 + 693 WP_003503184.1 ATP phosphoribosyltransferase -
G6L90_RS01550 (G6L90_01550) 325589..326035 - 447 WP_003503183.1 DoxX family protein -
G6L90_RS01555 (G6L90_01555) 326192..326626 - 435 WP_003503182.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10341.95 Da        Isoelectric Point: 10.6086

>T281857 WP_003503189.1 NZ_CP124967:c321422-321153 [Agrobacterium tumefaciens]
MIWKIEFQRAAVKQLGALTKSDANRIVSFLTDRIARDGNPRRTGAALQGSELGNFWRYRVGDYRIICDIQDHKLVVLVVE
IGHRREIYR

Download         Length: 270 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9212.31 Da        Isoelectric Point: 4.6044

>AT281857 WP_003503188.1 NZ_CP124967:c321639-321406 [Agrobacterium tumefaciens]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRQRIANKERTYTLEEVMRDLDLEN

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A846L580

Antitoxin

Source ID Structure
AlphaFold DB A0A822V377

References