Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 112586..113133 Replicon plasmid pAtAF1_95
Accession NZ_CP124965
Organism Agrobacterium fabacearum strain AF1/95

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G6L16_RS24200 Protein ID WP_174004674.1
Coordinates 112840..113133 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A7U5CZ68
Locus tag G6L16_RS24195 Protein ID WP_003519100.1
Coordinates 112586..112840 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L16_RS24185 (G6L16_024185) 108141..111254 + 3114 WP_284180582.1 efflux RND transporter permease subunit -
G6L16_RS24190 (G6L16_024190) 111462..112139 - 678 WP_174004672.1 SOS response-associated peptidase -
G6L16_RS24195 (G6L16_024195) 112586..112840 + 255 WP_003519100.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
G6L16_RS24200 (G6L16_024200) 112840..113133 + 294 WP_174004674.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6L16_RS24205 (G6L16_024205) 113299..113928 - 630 WP_174004676.1 plasmid pRiA4b ORF-3 family protein -
G6L16_RS24210 (G6L16_024210) 114070..115422 - 1353 WP_174004678.1 cytosine deaminase -
G6L16_RS24215 (G6L16_024215) 115454..116425 - 972 WP_174004680.1 LysR family transcriptional regulator -
G6L16_RS24220 (G6L16_024220) 116428..117423 - 996 WP_003517482.1 2-oxoglutarate and iron-dependent oxygenase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..804464 804464


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(6-64)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11207.92 Da        Isoelectric Point: 6.2160

>T281856 WP_174004674.1 NZ_CP124965:112840-113133 [Agrobacterium fabacearum]
MPFSLSVQAEEDIIFIAEEGIRIFGALVAKRYHDELFALLELIATNPRMARERHEISPPVRIHPFKAHLVVYRIIEDGSV
FVIRIRHGHEDWAGDSF

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9366.51 Da        Isoelectric Point: 9.8253

>AT281856 WP_003519100.1 NZ_CP124965:112586-112840 [Agrobacterium fabacearum]
MATMNVSLPDPMKDWVEAQAKTGRYSNASDYVRDLIRRDQARTDKIAEMQRFVDDGIRSGVGSRSTEELFALATSRAAIS
RGRA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U5CZ68

References