Detailed information of TA system TA028159

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PanAT/DUF4065(antitoxin)
• Location: 3650907..3651934
• Replicon: chromosome
• Accession: NC_018405
• Organism: Enterobacter cloacae subsp. cloacae ENHKU01

Toxin (Protein)

• Gene name: panT
• Uniprot ID: -
• Locus tag: ECENHK_RS22430
• Protein ID: WP_014884911.1
• Coordinates: 3650907..3651494 (-)
• Length: 196 a.a.

Antitoxin (Protein)

• Gene name: panA
• Uniprot ID: -
• Locus tag: ECENHK_RS17265
• Protein ID: WP_080021220.1
• Coordinates: 3651536..3651934 (-)
• Length: 133 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ECENHK_RS17235	3647144..3648193	+	1050	WP_014884907.1	phage portal protein	-
ECENHK_RS17240	3648230..3649093	-	864	WP_014884908.1	hypothetical protein	-
ECENHK_RS17245	3649103..3649774	-	672	WP_014884909.1	helix-turn-helix domain-containing protein	-
ECENHK_RS17250	3649793..3650602	-	810	WP_014884910.1	TIGR04255 family protein	-
ECENHK_RS22430	3650907..3651494	-	588	WP_014884911.1	hypothetical protein	Toxin
ECENHK_RS17265	3651536..3651934	-	399	WP_080021220.1	DUF4065 domain-containing protein	Antitoxin
ECENHK_RS17270	3652415..3652648	-	234	WP_014884913.1	DinI family protein	-
ECENHK_RS17275	3652659..3652847	-	189	WP_014884914.1	hypothetical protein	-
ECENHK_RS17280	3653007..3653702	-	696	WP_014884915.1	DNA adenine methylase	-
ECENHK_RS17285	3653854..3656148	-	2295	WP_014884916.1	replication endonuclease	-
ECENHK_RS23675	3656145..3656321	-	177	WP_187289095.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	3627766..3664399	36633

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Antitoxin SocA-like, Panacea domain (4-100)

Sequences

Toxin

Protein

• Length: 196 a.a.
• Molecular weight: 21839.54 Da
• Isoelectric Point: 4.5519

>T28159 WP_014884911.1 NC_018405:c3651494-3650907 [Enterobacter kobei]
MSIDNDLFESILRGAISANIDDLVKTITATEPQQPSKDSPQEEDDDVGDDKAQKEAQAFDTPTDDEHEELQALGYWSLSH
QRQVDSLTIQKSKEEIVRISCENDELRAKTKNNHAMARGRRIDNRLRLQMAAATFRFMQYWCCFVALVVFIYVAKNDGNP
PSEVIIALLGTSTISIVGLVGFVVSGLFKSNKDKE

Nucleotide

• Length: 588 bp

>T28159 NC_018405:c3651494-3650907 [Enterobacter kobei]
ATGTCCATTGATAACGATCTGTTCGAAAGCATACTTAGAGGCGCTATTAGCGCTAATATTGACGATCTTGTTAAAACTAT
CACTGCCACTGAGCCTCAACAGCCTTCTAAAGATTCCCCGCAAGAAGAAGATGATGATGTGGGAGATGATAAAGCTCAAA
AAGAGGCGCAAGCCTTTGATACTCCTACTGATGATGAGCATGAGGAACTTCAAGCATTAGGCTATTGGAGTTTGTCGCAT
CAAAGACAAGTTGATTCCTTGACTATACAAAAGTCTAAAGAAGAAATTGTTCGGATTAGTTGCGAAAATGACGAGTTGCG
AGCAAAAACAAAGAATAACCATGCTATGGCTAGAGGGCGACGTATCGATAATCGGTTACGTTTGCAGATGGCTGCTGCTA
CGTTCCGTTTCATGCAATACTGGTGTTGCTTTGTTGCATTAGTGGTCTTCATTTACGTAGCAAAAAATGACGGTAATCCC
CCCAGTGAAGTAATAATTGCTCTCCTTGGAACAAGCACGATTAGCATTGTTGGTTTGGTTGGTTTTGTGGTCAGTGGATT
ATTTAAAAGTAATAAAGATAAAGAGTAG

Antitoxin

Protein

• Length: 133 a.a.
• Molecular weight: 14970.23 Da
• Isoelectric Point: 6.7100

>AT28159 WP_080021220.1 NC_018405:c3651934-3651536 [Enterobacter kobei]
MQAQKLLYIAHGYSLAFLNEPLLEEPVCAWRYGPVIPSVYYALRHNRSEPIADKAPTTAIETETLDSKTASLLDMVYETY
GKLSGVVLSEFTHRPGTPWYQAMVKRENIISDASIKDYYLKLIKRDPVCNGL

Nucleotide

• Length: 399 bp

>AT28159 NC_018405:c3651934-3651536 [Enterobacter kobei]
ATGCAGGCCCAGAAACTGCTGTACATAGCTCATGGCTATAGCTTAGCGTTTCTAAATGAGCCTTTGCTTGAAGAACCCGT
GTGTGCGTGGAGGTATGGTCCGGTCATACCGTCCGTGTATTATGCTCTGCGTCACAATCGTTCTGAACCGATTGCAGATA
AGGCACCGACAACTGCAATTGAAACAGAAACCTTAGATAGCAAAACAGCTTCTTTGCTTGATATGGTTTACGAAACTTAT
GGCAAGCTTTCTGGAGTTGTTCTCTCTGAGTTTACACACCGTCCGGGTACACCTTGGTATCAAGCCATGGTCAAGAGAGA
GAATATAATCAGTGACGCAAGTATCAAAGATTACTATCTAAAACTGATAAAGCGTGACCCGGTTTGCAACGGATTGTAA