Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-GNAT
Location 590612..591432 Replicon chromosome
Accession NC_018405
Organism Enterobacter cloacae subsp. cloacae ENHKU01

Toxin (Protein)


Gene name yjhX Uniprot ID -
Locus tag ECENHK_RS02805 Protein ID WP_014882342.1
Coordinates 591175..591432 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag ECENHK_RS02800 Protein ID WP_014882341.1
Coordinates 590612..591163 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECENHK_RS02770 585688..586287 - 600 WP_014882333.1 DUF1819 family protein -
ECENHK_RS02775 587134..587454 + 321 WP_014882335.1 hypothetical protein -
ECENHK_RS02780 587512..588450 - 939 WP_014882336.1 glycosyltransferase -
ECENHK_RS02785 588995..589387 - 393 WP_014882338.1 VOC family protein -
ECENHK_RS02790 589435..589686 - 252 WP_014882339.1 hypothetical protein -
ECENHK_RS02795 589814..590560 - 747 WP_014882340.1 class I SAM-dependent methyltransferase -
ECENHK_RS02800 590612..591163 - 552 WP_014882341.1 N-acetyltransferase Antitoxin
ECENHK_RS02805 591175..591432 - 258 WP_014882342.1 YjhX family toxin Toxin
ECENHK_RS02810 591758..593020 - 1263 WP_014882343.1 PTS galactitol transporter subunit IIC -
ECENHK_RS02815 593109..594104 - 996 WP_000649881.1 2-hydroxyacid dehydrogenase -
ECENHK_RS02820 594121..594882 - 762 WP_014882344.1 SDR family oxidoreductase -
ECENHK_RS02825 594894..596432 - 1539 WP_014882345.1 carbohydrate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 565653..619208 53555


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(19-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T28147 WP_014882342.1 NC_018405:c591432-591175 [Enterobacter kobei]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T28147 NC_018405:c591432-591175 [Enterobacter kobei]
ATGAATTTATCCCGTCAGGAACAACGTACTTTACACGTTCTCGCCAAAGGTGGCCGAATCGCGCACGTCCGCGATGCTTC
AGGCCGCGTCACCTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGGTCTGAATAACGTTCGCGCC
CAGCTCGATAATCGCTAA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20261.21 Da        Isoelectric Point: 6.8222

>AT28147 WP_014882341.1 NC_018405:c591163-590612 [Enterobacter kobei]
MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDESARPALSLLARHEGKAVGHILFTRATFKGVSDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRQMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEKHKACWMMQSLAA
QPMNVTGNIQCAQALMKPEHWRE

Download         Length: 552 bp

>AT28147 NC_018405:c591163-590612 [Enterobacter kobei]
ATGACAGCACACCACTTCACTTTTCAAATCACAGATGAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCTGATTTAACGGCCTCTTTACTTGAAGATGAAAGCGCGCGCCCTGCGTTATCGCTGCTGGCCC
GACATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCGACCTTCAAAGGAGTAAGCGATTCACCGCTGATGCAT
ATCCTTGCTCCCCTGGCGGTCATACCGGAATACCAGGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGCAAATGGGCTGCCAGACGGTATTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGATTTGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGAAGCATAAAGCCTGCTGGATGATGCAATCACTCGCCGCT
CAGCCCATGAACGTGACCGGCAACATCCAGTGCGCGCAGGCCCTGATGAAACCGGAGCACTGGCGTGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References