Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
Location | 590612..591432 | Replicon | chromosome |
Accession | NC_018405 | ||
Organism | Enterobacter cloacae subsp. cloacae ENHKU01 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | - |
Locus tag | ECENHK_RS02805 | Protein ID | WP_014882342.1 |
Coordinates | 591175..591432 (-) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | - |
Locus tag | ECENHK_RS02800 | Protein ID | WP_014882341.1 |
Coordinates | 590612..591163 (-) | Length | 184 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ECENHK_RS02770 | 585688..586287 | - | 600 | WP_014882333.1 | DUF1819 family protein | - |
ECENHK_RS02775 | 587134..587454 | + | 321 | WP_014882335.1 | hypothetical protein | - |
ECENHK_RS02780 | 587512..588450 | - | 939 | WP_014882336.1 | glycosyltransferase | - |
ECENHK_RS02785 | 588995..589387 | - | 393 | WP_014882338.1 | VOC family protein | - |
ECENHK_RS02790 | 589435..589686 | - | 252 | WP_014882339.1 | hypothetical protein | - |
ECENHK_RS02795 | 589814..590560 | - | 747 | WP_014882340.1 | class I SAM-dependent methyltransferase | - |
ECENHK_RS02800 | 590612..591163 | - | 552 | WP_014882341.1 | N-acetyltransferase | Antitoxin |
ECENHK_RS02805 | 591175..591432 | - | 258 | WP_014882342.1 | YjhX family toxin | Toxin |
ECENHK_RS02810 | 591758..593020 | - | 1263 | WP_014882343.1 | PTS galactitol transporter subunit IIC | - |
ECENHK_RS02815 | 593109..594104 | - | 996 | WP_000649881.1 | 2-hydroxyacid dehydrogenase | - |
ECENHK_RS02820 | 594121..594882 | - | 762 | WP_014882344.1 | SDR family oxidoreductase | - |
ECENHK_RS02825 | 594894..596432 | - | 1539 | WP_014882345.1 | carbohydrate kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 565653..619208 | 53555 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9552.07 Da Isoelectric Point: 11.1381
>T28147 WP_014882342.1 NC_018405:c591432-591175 [Enterobacter kobei]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR
Download Length: 258 bp
>T28147 NC_018405:c591432-591175 [Enterobacter kobei]
ATGAATTTATCCCGTCAGGAACAACGTACTTTACACGTTCTCGCCAAAGGTGGCCGAATCGCGCACGTCCGCGATGCTTC
AGGCCGCGTCACCTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGGTCTGAATAACGTTCGCGCC
CAGCTCGATAATCGCTAA
ATGAATTTATCCCGTCAGGAACAACGTACTTTACACGTTCTCGCCAAAGGTGGCCGAATCGCGCACGTCCGCGATGCTTC
AGGCCGCGTCACCTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGGTCTGAATAACGTTCGCGCC
CAGCTCGATAATCGCTAA
Antitoxin
Download Length: 184 a.a. Molecular weight: 20261.21 Da Isoelectric Point: 6.8222
>AT28147 WP_014882341.1 NC_018405:c591163-590612 [Enterobacter kobei]
MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDESARPALSLLARHEGKAVGHILFTRATFKGVSDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRQMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEKHKACWMMQSLAA
QPMNVTGNIQCAQALMKPEHWRE
MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDESARPALSLLARHEGKAVGHILFTRATFKGVSDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRQMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEKHKACWMMQSLAA
QPMNVTGNIQCAQALMKPEHWRE
Download Length: 552 bp
>AT28147 NC_018405:c591163-590612 [Enterobacter kobei]
ATGACAGCACACCACTTCACTTTTCAAATCACAGATGAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCTGATTTAACGGCCTCTTTACTTGAAGATGAAAGCGCGCGCCCTGCGTTATCGCTGCTGGCCC
GACATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCGACCTTCAAAGGAGTAAGCGATTCACCGCTGATGCAT
ATCCTTGCTCCCCTGGCGGTCATACCGGAATACCAGGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGCAAATGGGCTGCCAGACGGTATTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGATTTGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGAAGCATAAAGCCTGCTGGATGATGCAATCACTCGCCGCT
CAGCCCATGAACGTGACCGGCAACATCCAGTGCGCGCAGGCCCTGATGAAACCGGAGCACTGGCGTGAATAA
ATGACAGCACACCACTTCACTTTTCAAATCACAGATGAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCTGATTTAACGGCCTCTTTACTTGAAGATGAAAGCGCGCGCCCTGCGTTATCGCTGCTGGCCC
GACATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCGACCTTCAAAGGAGTAAGCGATTCACCGCTGATGCAT
ATCCTTGCTCCCCTGGCGGTCATACCGGAATACCAGGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGCAAATGGGCTGCCAGACGGTATTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGATTTGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGAAGCATAAAGCCTGCTGGATGATGCAATCACTCGCCGCT
CAGCCCATGAACGTGACCGGCAACATCCAGTGCGCGCAGGCCCTGATGAAACCGGAGCACTGGCGTGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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