Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1924685..1924830 Replicon chromosome
Accession NZ_CP124873
Organism Klebsiella pneumoniae strain K82

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1924721..1924823 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1924685..1924830 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QKW38_RS09485 1919815..1921875 + 2061 WP_004151449.1 oligopeptidase B -
QKW38_RS09490 1921879..1922538 - 660 WP_002911407.1 exodeoxyribonuclease X -
QKW38_RS09495 1922617..1922847 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QKW38_RS09500 1922960..1923334 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QKW38_RS09505 1923338..1924207 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
QKW38_RS09510 1924224..1924562 + 339 WP_002911404.1 YebY family protein -
- 1924685..1924830 - 146 - - Antitoxin
- 1924721..1924823 + 103 - - Toxin
QKW38_RS09515 1925198..1925341 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QKW38_RS09520 1925446..1926414 - 969 WP_004151446.1 VirK/YbjX family protein -
QKW38_RS09525 1926571..1927224 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
QKW38_RS09530 1927221..1927412 - 192 WP_002911395.1 YebW family protein -
QKW38_RS09535 1927510..1927749 - 240 WP_002911393.1 YebV family protein -
QKW38_RS09540 1927865..1929298 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T281372 NZ_CP124873:1924721-1924823 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT281372 NZ_CP124873:c1924830-1924685 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References