Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 804522..805179 Replicon chromosome
Accession NZ_CP124866
Organism Klebsiella quasipneumoniae strain M7

Toxin (Protein)


Gene name cptA Uniprot ID A0A2A5MNX1
Locus tag QJS48_RS04010 Protein ID WP_004205323.1
Coordinates 804769..805179 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID W8UQ37
Locus tag QJS48_RS04005 Protein ID WP_002916312.1
Coordinates 804522..804788 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJS48_RS03980 (799725) 799725..801158 - 1434 WP_004205314.1 6-phospho-beta-glucosidase BglA -
QJS48_RS03985 (801277) 801277..802005 - 729 WP_004205316.1 MurR/RpiR family transcriptional regulator -
QJS48_RS03990 (802055) 802055..802366 + 312 WP_004205318.1 N(4)-acetylcytidine aminohydrolase -
QJS48_RS03995 (802529) 802529..803188 + 660 WP_004205319.1 hemolysin III family protein -
QJS48_RS04000 (803293) 803293..804276 - 984 WP_049116109.1 tRNA-modifying protein YgfZ -
QJS48_RS04005 (804522) 804522..804788 + 267 WP_002916312.1 FAD assembly factor SdhE Antitoxin
QJS48_RS04010 (804769) 804769..805179 + 411 WP_004205323.1 protein YgfX Toxin
QJS48_RS04015 (805186) 805186..805707 - 522 WP_004205324.1 flavodoxin FldB -
QJS48_RS04020 (805808) 805808..806704 + 897 WP_004144729.1 site-specific tyrosine recombinase XerD -
QJS48_RS04025 (806727) 806727..807440 + 714 WP_004205326.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QJS48_RS04030 (807446) 807446..809179 + 1734 WP_017899799.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16035.83 Da        Isoelectric Point: 11.4778

>T281355 WP_004205323.1 NZ_CP124866:804769-805179 [Klebsiella quasipneumoniae]
VVLWQSDLRISWRAQWFSLLLHGVVAALVLLVPWPLSYTPIWLLLLSLVVFDCVRSQRRIHARRGEIKLLTDSRLRWQNA
DWEILGTPWVINSGMLLRLRHVDTRRGQHLWLAADSMDAGEWRDLRRLVLQKPAQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10480.98 Da        Isoelectric Point: 5.1116

>AT281355 WP_002916312.1 NZ_CP124866:804522-804788 [Klebsiella quasipneumoniae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDADKQLFIRLLENDDPDLFNWLMNHGKPADAELQRMVTLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2A5MNX1

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3GY41

References