Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 1812467..1812992 Replicon chromosome
Accession NZ_CP124863
Organism Streptomyces sp. BPTC-684

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QIY60_RS07975 Protein ID WP_054221840.1
Coordinates 1812729..1812992 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S5UWF1
Locus tag QIY60_RS07970 Protein ID WP_019434848.1
Coordinates 1812467..1812736 (+) Length 90 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QIY60_RS07970 (QIY60_07970) 1812467..1812736 + 270 WP_019434848.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QIY60_RS07975 (QIY60_07975) 1812729..1812992 + 264 WP_054221840.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QIY60_RS07980 (QIY60_07980) 1813127..1814215 - 1089 WP_283141768.1 redox-regulated ATPase YchF -
QIY60_RS07985 (QIY60_07985) 1814465..1815058 + 594 WP_283141769.1 hypothetical protein -
QIY60_RS07990 (QIY60_07990) 1815216..1815956 - 741 WP_283141770.1 ROK family protein -
QIY60_RS07995 (QIY60_07995) 1816052..1817032 - 981 WP_283141771.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 88 a.a.        Molecular weight: 10098.57 Da        Isoelectric Point: 8.5042

>T281354 WP_054221840.1 NZ_CP124863:1812729-1812992 [Streptomyces sp. BPTC-684]
VSEYRTVFRPEAQAELRKIPRDMALRILAKLTELETDPLGFNTTALVSQPERRRLRVGDYRVVYTIDNGELVVWVVHVGH
RSTVYET

Download         Length: 264 bp


Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10259.71 Da        Isoelectric Point: 4.6265

>AT281354 WP_019434848.1 NZ_CP124863:1812467-1812736 [Streptomyces sp. BPTC-684]
MTQPLPIESIRDVRAHLAEVVERADRDDVPTVITRRGKEVAAVVSIEVLRKYQEWEEREINRIIDERMANPAPGIPIEDI
MRETLARGE

Download         Length: 270 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB S5UWF1

References