Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1172247..1172789 Replicon chromosome
Accession NZ_CP124855
Organism Chryseobacterium sp. wcd7

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QGN23_RS05340 Protein ID WP_282905970.1
Coordinates 1172538..1172789 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QGN23_RS05335 Protein ID WP_282905969.1
Coordinates 1172247..1172531 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QGN23_RS05315 (QGN23_05315) 1167597..1168961 + 1365 WP_282905965.1 M20/M25/M40 family metallo-hydrolase -
QGN23_RS05320 (QGN23_05320) 1168961..1169314 + 354 WP_282905966.1 diacylglycerol kinase family protein -
QGN23_RS05325 (QGN23_05325) 1169298..1170083 - 786 WP_282905967.1 patatin-like phospholipase family protein -
QGN23_RS05330 (QGN23_05330) 1170154..1172091 - 1938 WP_282905968.1 alpha/beta fold hydrolase -
QGN23_RS05335 (QGN23_05335) 1172247..1172531 - 285 WP_282905969.1 putative addiction module antidote protein Antitoxin
QGN23_RS05340 (QGN23_05340) 1172538..1172789 - 252 WP_282905970.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QGN23_RS05345 (QGN23_05345) 1173158..1174549 - 1392 WP_282905971.1 dihydrolipoyl dehydrogenase -
QGN23_RS05350 (QGN23_05350) 1174923..1175588 - 666 WP_282905972.1 response regulator -
QGN23_RS05355 (QGN23_05355) 1175589..1175777 - 189 WP_282905973.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-82)

Antitoxin

Uncharacterized protein HI1420

(3-89)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9655.46 Da        Isoelectric Point: 10.4153

>T281351 WP_282905970.1 NZ_CP124855:c1172789-1172538 [Chryseobacterium sp. wcd7]
MKDVTAKAKILFRIQKLENDEHLGDFKPVGNGINKLKFNYAKGYRIYFMEIDGKIIILLIGGDKSTQQKDIEKAKEIWKK
LKK

Download         Length: 252 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 9980.41 Da        Isoelectric Point: 4.7616

>AT281351 WP_282905969.1 NZ_CP124855:c1172531-1172247 [Chryseobacterium sp. wcd7]
MNTSKFDIADYLDSNEMIAEYLNAALEEGNESEIIAAIGNVAKAIGMTKIAEETGLSRPSLYKALSEGAKPQFATIMKVL
KAVGGHIHINPATA

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References