281347

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1625559..1627273 Replicon chromosome
Accession NZ_CP124841
Organism Aeromonas salmonicida strain 57

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag QLQ87_RS07410 Protein ID WP_282684457.1
Coordinates 1626620..1627273 (-) Length 218 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag QLQ87_RS07405 Protein ID WP_103828953.1
Coordinates 1625559..1626623 (-) Length 355 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ87_RS07390 (QLQ87_07390) 1620683..1621621 + 939 WP_171269279.1 restriction endonuclease -
QLQ87_RS07395 (QLQ87_07395) 1621640..1622353 - 714 WP_005331303.1 SprT family zinc-dependent metalloprotease -
QLQ87_RS07400 (QLQ87_07400) 1622353..1625484 - 3132 WP_282684456.1 HsdR family type I site-specific deoxyribonuclease -
QLQ87_RS07405 (QLQ87_07405) 1625559..1626623 - 1065 WP_103828953.1 macro domain-containing protein Antitoxin
QLQ87_RS07410 (QLQ87_07410) 1626620..1627273 - 654 WP_282684457.1 DUF4433 domain-containing protein Toxin
QLQ87_RS07415 (QLQ87_07415) 1627529..1628806 - 1278 WP_282684458.1 restriction endonuclease subunit S -
QLQ87_RS07420 (QLQ87_07420) 1628806..1631253 - 2448 WP_282684459.1 type I restriction-modification system subunit M -
QLQ87_RS07425 (QLQ87_07425) 1631439..1631996 - 558 WP_025201140.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-216)

Antitoxin

Macro domain

(18-131)


Sequences

Toxin        


Download         Length: 218 a.a.        Molecular weight: 25376.97 Da        Isoelectric Point: 7.0177

>T281347 WP_282684457.1 NZ_CP124841:c1627273-1626620 [Aeromonas salmonicida]
MAYDYSQSLNPEKALIFRIVHRDNLEWILTHGLWAGNGQQQNSHWVHIGLPELIAKRARHPVPLAPYGVLNDYVPFYFTP
FSPMLSNIHSGRGVPRRENDEILILVSSLHRMAELGLPFVFTDSHAYYQWANFYVDLGDLGRIDWPLLQRRDFKRDAEDL
SKLERYQAEALIHQHCPIEALLGVVCYNEEIKNRVEQCMNRVGVARPVYVRDGWYFR

Download         Length: 654 bp

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 39597.71 Da        Isoelectric Point: 6.6471

>AT281347 WP_103828953.1 NZ_CP124841:c1626623-1625559 [Aeromonas salmonicida]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPANMRAYAEACKQGDVVTGKMFITQTGELLGPRWIVNFPTK
QHWRNPAQMAWIQDGLQDLRAWLQAQQVSSIAIPPLGAGNGGLPWPEVKQAIETALGDLDIDILLYEPSSQYQNVAKRGG
VAELTPARALIAELVRRYWFLGMECSLLEIQKLAWFLARVIGRNPLGDPLQLQFKAHRYGPYANNLTHLLNAMDGSYLQS
DKRIPDSKPFDVIWFNEAKKQELAVYLHTEAKAFLPILEQTTALIDGFESPYGMELLATVDWLIAEEGCAPTLSALREGL
HRWPAGTPWGERKARLFDDRSLQIALTRLQQGLV

Download         Length: 1065 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References