Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2034591..2034736 Replicon chromosome
Accession NZ_CP124837
Organism Klebsiella pneumoniae strain KPN6328

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2034627..2034729 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2034591..2034736 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QHR28_RS09990 (QHR28_09990) 2029721..2031781 + 2061 WP_004151449.1 oligopeptidase B -
QHR28_RS09995 (QHR28_09995) 2031785..2032444 - 660 WP_002911407.1 exodeoxyribonuclease X -
QHR28_RS10000 (QHR28_10000) 2032523..2032753 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QHR28_RS10005 (QHR28_10005) 2032866..2033240 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QHR28_RS10010 (QHR28_10010) 2033244..2034113 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
QHR28_RS10015 (QHR28_10015) 2034130..2034468 + 339 WP_002911404.1 YebY family protein -
- 2034591..2034736 - 146 - - Antitoxin
- 2034627..2034729 + 103 - - Toxin
QHR28_RS10020 (QHR28_10020) 2035104..2035247 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QHR28_RS10025 (QHR28_10025) 2035352..2036320 - 969 WP_004151446.1 VirK/YbjX family protein -
QHR28_RS10030 (QHR28_10030) 2036477..2037130 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QHR28_RS10035 (QHR28_10035) 2037127..2037318 - 192 WP_002911395.1 YebW family protein -
QHR28_RS10040 (QHR28_10040) 2037416..2037655 - 240 WP_002911393.1 YebV family protein -
QHR28_RS10045 (QHR28_10045) 2037771..2039204 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T281332 NZ_CP124837:2034627-2034729 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT281332 NZ_CP124837:c2034736-2034591 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References