Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1928990..1929134 Replicon chromosome
Accession NZ_CP124827
Organism Klebsiella pneumoniae strain K147

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1929026..1929128 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1928990..1929134 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLG19_RS09335 (QLG19_09335) 1924120..1926180 + 2061 WP_004151449.1 oligopeptidase B -
QLG19_RS09340 (QLG19_09340) 1926184..1926843 - 660 WP_002911407.1 exodeoxyribonuclease X -
QLG19_RS09345 (QLG19_09345) 1926922..1927152 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QLG19_RS09350 (QLG19_09350) 1927265..1927639 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QLG19_RS09355 (QLG19_09355) 1927643..1928512 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
QLG19_RS09360 (QLG19_09360) 1928529..1928867 + 339 WP_002911404.1 YebY family protein -
- 1928990..1929134 - 145 - - Antitoxin
- 1929026..1929128 + 103 - - Toxin
QLG19_RS09365 (QLG19_09365) 1929261..1929542 - 282 Protein_1828 tyrosine-type recombinase/integrase -
QLG19_RS09370 (QLG19_09370) 1929619..1930098 + 480 WP_032419797.1 lysis protein -
QLG19_RS09375 (QLG19_09375) 1930553..1930748 + 196 Protein_1830 DNA polymerase V -
QLG19_RS09380 (QLG19_09380) 1930887..1932392 + 1506 WP_020956680.1 hypothetical protein -
QLG19_RS09385 (QLG19_09385) 1932642..1933070 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
QLG19_RS09390 (QLG19_09390) 1933080..1933361 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T281316 NZ_CP124827:1929026-1929128 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT281316 NZ_CP124827:c1929134-1928990 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References