Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1860897..1861042 Replicon chromosome
Accession NZ_CP124824
Organism Klebsiella pneumoniae strain H53

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1860933..1861035 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1860897..1861042 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLG18_RS09105 1856027..1858087 + 2061 WP_004151449.1 oligopeptidase B -
QLG18_RS09110 1858091..1858750 - 660 WP_021440386.1 exodeoxyribonuclease X -
QLG18_RS09115 1858829..1859059 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QLG18_RS09120 1859172..1859546 + 375 WP_201524362.1 CopC domain-containing protein YobA -
QLG18_RS09125 1859550..1860419 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
QLG18_RS09130 1860436..1860774 + 339 WP_002911404.1 YebY family protein -
- 1860897..1861042 - 146 - - Antitoxin
- 1860933..1861035 + 103 - - Toxin
QLG18_RS09135 1861410..1861553 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QLG18_RS09140 1861658..1862626 - 969 WP_004151446.1 VirK/YbjX family protein -
QLG18_RS09145 1862783..1863436 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QLG18_RS09150 1863433..1863624 - 192 WP_002911395.1 YebW family protein -
QLG18_RS09155 1863722..1863961 - 240 WP_002911393.1 YebV family protein -
QLG18_RS09160 1864077..1865510 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T281297 NZ_CP124824:1860933-1861035 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT281297 NZ_CP124824:c1861042-1860897 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References