Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 2860513..2861108 Replicon chromosome
Accession NZ_CP124819
Organism Escherichia coli strain C325

Toxin (Protein)


Gene name chpB Uniprot ID U9Y4M4
Locus tag QLG17_RS14390 Protein ID WP_000239579.1
Coordinates 2860513..2860863 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag QLG17_RS14395 Protein ID WP_052915232.1
Coordinates 2860857..2861108 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLG17_RS14370 (2855959) 2855959..2856981 - 1023 WP_001400707.1 ABC transporter permease -
QLG17_RS14375 (2856995) 2856995..2858497 - 1503 WP_052915233.1 sugar ABC transporter ATP-binding protein -
QLG17_RS14380 (2858637) 2858637..2859593 - 957 WP_000265940.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
QLG17_RS14385 (2859903) 2859903..2860433 + 531 WP_000055075.1 inorganic diphosphatase -
QLG17_RS14390 (2860513) 2860513..2860863 - 351 WP_000239579.1 endoribonuclease toxin ChpB Toxin
QLG17_RS14395 (2860857) 2860857..2861108 - 252 WP_052915232.1 type II toxin-antitoxin system antitoxin ChpS Antitoxin
QLG17_RS14400 (2861320) 2861320..2861661 - 342 WP_001219160.1 gamma-glutamylcyclotransferase -
QLG17_RS14405 (2861664) 2861664..2865443 - 3780 WP_033810330.1 autotransporter assembly complex protein TamB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12511.45 Da        Isoelectric Point: 5.6219

>T281277 WP_000239579.1 NZ_CP124819:c2860863-2860513 [Escherichia coli]
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLRARLAKRIGLAADEVVEEALLRLQAVVE

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9301.61 Da        Isoelectric Point: 4.4201

>AT281277 WP_052915232.1 NZ_CP124819:c2861108-2860857 [Escherichia coli]
MRITIKRWGNSTGMVIPNIVMKELNLQPGQSVEAQVSNNQLILTPISRRYSLDELLAQCDMNAAELSEQDVWGKSTPAGD
EIW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0Y8A8

Antitoxin

Source ID Structure

References