Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 567051..567567 Replicon chromosome
Accession NZ_CP124813
Organism Citrobacter freundii strain CF12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QLG15_RS02865 Protein ID WP_044699148.1
Coordinates 567283..567567 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0J1MV10
Locus tag QLG15_RS02860 Protein ID WP_003839576.1
Coordinates 567051..567293 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLG15_RS02840 (562066) 562066..563199 + 1134 WP_016149471.1 amidohydrolase/deacetylase family metallohydrolase -
QLG15_RS02845 (563183) 563183..564301 + 1119 WP_044699152.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
QLG15_RS02850 (564298) 564298..565038 + 741 WP_044699149.1 KDGP aldolase family protein -
QLG15_RS02855 (565060) 565060..566973 + 1914 WP_003839574.1 BglG family transcription antiterminator -
QLG15_RS02860 (567051) 567051..567293 + 243 WP_003839576.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QLG15_RS02865 (567283) 567283..567567 + 285 WP_044699148.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QLG15_RS02870 (567571) 567571..568035 - 465 WP_032937736.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
QLG15_RS02875 (568142) 568142..570280 - 2139 WP_003025782.1 anaerobic ribonucleoside-triphosphate reductase -
QLG15_RS02880 (570658) 570658..571242 - 585 WP_003839584.1 fructose PTS transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10865.69 Da        Isoelectric Point: 10.1988

>T281257 WP_044699148.1 NZ_CP124813:567283-567567 [Citrobacter freundii]
MTYELEFDPRALKEWHKLGDTVKAQFKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDEVVTVFVVAVGK
RQHSAVYLDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT281257 WP_003839576.1 NZ_CP124813:567051-567293 [Citrobacter freundii]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTVSDSEDTLIQTVRERLASPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0J1MV10

References