281249

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 4084026..4084687 Replicon chromosome
Accession NZ_CP124809
Organism Citrobacter freundii strain CF13

Toxin (Protein)


Gene name ypjF Uniprot ID S3IMJ6
Locus tag QLG16_RS19735 Protein ID WP_000698542.1
Coordinates 4084026..4084349 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag QLG16_RS19740 Protein ID WP_167736232.1
Coordinates 4084370..4084687 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLG16_RS19710 (4079368) 4079368..4079946 + 579 WP_044700788.1 tyrosine-type recombinase/integrase -
QLG16_RS19715 (4080040) 4080040..4080237 + 198 WP_044700790.1 hypothetical protein -
QLG16_RS19720 (4080219) 4080219..4080527 + 309 WP_170864030.1 hypothetical protein -
QLG16_RS19725 (4080935) 4080935..4081432 - 498 WP_044700793.1 hypothetical protein -
QLG16_RS19730 (4081756) 4081756..4082924 + 1169 WP_100216202.1 IS3 family transposase -
QLG16_RS19735 (4084026) 4084026..4084349 - 324 WP_000698542.1 TA system toxin CbtA family protein Toxin
QLG16_RS19740 (4084370) 4084370..4084687 - 318 WP_167736232.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
QLG16_RS19745 (4084706) 4084706..4084927 - 222 WP_000691995.1 DUF987 domain-containing protein -
QLG16_RS19750 (4084936) 4084936..4085412 - 477 WP_000811694.1 RadC family protein -
QLG16_RS19755 (4085428) 4085428..4085886 - 459 WP_016538084.1 antirestriction protein -
QLG16_RS19760 (4085972) 4085972..4086208 - 237 WP_000004273.1 DUF905 domain-containing protein -
QLG16_RS19765 (4086286) 4086286..4086696 - 411 WP_000912997.1 hypothetical protein -
QLG16_RS19770 (4086763) 4086763..4087200 - 438 WP_024198335.1 hypothetical protein -
QLG16_RS19775 (4087242) 4087242..4087778 - 537 WP_000219797.1 DUF4339 domain-containing protein -
QLG16_RS19780 (4087804) 4087804..4088514 - 711 WP_024198336.1 hypothetical protein -
QLG16_RS19785 (4088723) 4088723..4089547 - 825 WP_000197385.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4075404..4124216 48812


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-107)

Antitoxin

Antitoxin CbeA

(6-104)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12350.38 Da        Isoelectric Point: 8.9789

>T281249 WP_000698542.1 NZ_CP124809:c4084349-4084026 [Citrobacter freundii]
MKILPATISRAAKPCLPPVAVWQLLLTRLLEKHYGLTLNDTPFSDETVIKEHFDAGITLANAINFLVEKYELVRIDRRGF
SWQEQTPYLTNIDIMRARRDLGLLNRN

Download         Length: 324 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11816.47 Da        Isoelectric Point: 6.9367

>AT281249 WP_167736232.1 NZ_CP124809:c4084687-4084370 [Citrobacter freundii]
MSNIIWGLQRDITPRLGTRLVQEGNQLHYLADRACITGKFSDAECLKLDVAFPHFISRMESMLSTGEMNPRHAHCVTLYH
NGFTCEADTLGSCGYVYVAVYSSQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S3IMJ6

Antitoxin

Source ID Structure

References